Progress and Promise in Parkinson’s Disease

06.07.10 / parkinson disease / Author: Alex
Tags: Disease, parkinsons, Progress, Promise

Parkinson’s disease is a neurodegenerative disease that affects nearly a million people in the United States. The symptoms include tremors, slow movement, muscle rigidity and less facial expression. No cure exists for the disease and current medications become less effective over time. William Langston, CEO and scientific director of the Parkinson’s Institute, discusses stem cell-based research strategies to better understand the disease and to find new therapies. The Parkinson’s Institute has an Early Translation grant from CIRM.

Parkinsons Disease Causes Symptoms Information With Treatment

Parkinson’s is found all over the world. Exact global figures are not always available, though it is estimated that four million people worldwide have the condition. Parkinson’s disease belongs to a group of conditions called movement disorders. Parkinson’s disease afflicts 1 to 1 1/2 million people in the United States. The disorder occurs in all races but is somewhat more prevalent among Caucasians. People with the disease may have trouble walking, talking or doing simple tasks. Dysfunctional antioxidative mechanisms are associated with older age as well, suggesting that the acceleration of age-related changes in dopamine production may be a factor. Parkinson’s disease patients have at least one relative with parkinsonian symptoms, suggesting that a genetic factor may be involved. There is no cure for Parkinson’s at present, drugs are used to try to control symptoms of Parkinson’s. The most widely used form of treatment is L-dopa in various forms. L-dopa is transformed into dopamine in the dopaminergic neurons by L-aromatic amino acid decarboxylase (often known by its former name dopa-decarboxylase). The most widely practiced treatment for the speech disorders associated with Parkinson’s disease is Lee Silverman Voice Treatment (LSVT). LSVT focuses on increasing vocal loudness. Regular physical exercise and/or therapy can be beneficial to the patient for maintaining and improving mobility, flexibility, balance and a range of motion. Nutrients have been used in clinical studies and are widely used by people with Parkinson’s disease in order to partially treat PD or slow down its deterioration.

Causes of Parkinsons Disease

Common Causes and Risk factors of Parkinsons Disease

Free radicals.

Accelerated aging.

Environmental toxins.

Genetic factors.

Trauma.

Carbon monoxide poisoning.

Hydrocephalus.

Signs and Symptoms of Parkinsons Disease

Common Sign and Symptoms of Parkinsons Disease

Depression and other emotional changes.

Difficulty in swallowing.

Chewing, and speaking.

Urinary problems.

Constipation.

Skin problems.

Sleep disruptions. 

Trembling of hands, arms, legs, jaw and face.

Treatment of Parkinsons Disease

Common Treatment of Parkinsons Disease

Successful treatment of Parkinson’s disease involves much more than just the use of drugs. Levodopa and carbidopa combined (Sinemet) is the mainstay of Parkinson’s therapy.

Tolcapone inhibits the COMT enzyme, thereby prolonging the effects of L-dopa, and so has been used to complement L-dopa.

The most widely practiced treatment for the speech disorders associated with Parkinson’s disease is Lee Silverman Voice Treatment (LSVT).

Nutrients have been used in clinical studies and are widely used by people with Parkinson’s disease in order to partially treat PD or slow down its deterioration.

Catechol O-methyl transferase (COMT) inhibitors act by inhibiting catabolism of dopamine, thereby extending L-dopa’s peripheral half-life.

Surgical treatment for PD is generally considered for patients who respond to medications.

Azilect was approved for use as an initial single drug therapy in early Parkinson’s disease. Azilect (rasagiline), a new molecular entity, for the treatment of Parkinson’s disease.

Physical therapy can help strengthen and tone underused muscles, and give rigid muscles a better range of motion.

Parkinson’s Disease: A Complete Guide for Patients and Families, Second Edition (A Johns Hopkins Press Health Book)

• ISBN13: 9780801885464
• Condition: NEW
• Notes: Brand New from Publisher. No Remainder Mark.

Recent innovations, including deep brain stimulation and new medications, have significantly improved the lives of people with Parkinson’s disease. Nevertheless, medical, emotional, and physical challenges remain. The second edition of this accessible and comprehensive guide provides crucial information for managing this complex condition, including details on the use of medications, diet, exercise, complementary therapies, and surgery. The second edition includes new information about:• The g

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Parkinson’s Disease Foundation Announces Research Awards Totaling .2 Million
The Parkinson’s Disease Foundation (PDF) is pleased to announce awards totaling .2 million for research projects designed to understand the cause(s) of and find a cure for Parkinson’s disease (PD). The awards will support the work of 15 leading scientists and are provided through two key PDF research programs, International Research Grants and Research Fellowship Grants…
Read more on Medical News Today

Question by Bigbird333: How does parkinson disease affect cells of the body?
and what cells of the body does parkinson disease affect?
thanks and NO STUIPID ANSWERS! i need it for a project that is due tommorow!

Best answer:

Answer by Doctor J
Parkinson’s disease results from loss of dopamine producing cells in the part of the brain called the Substantia Nigra.

Give your answer to this question below!