suffers from Parkinson's disease, then this is going to be one of the most important things you'll ever read.Progress and Promise in Parkinson’s Disease
06.07.10 / parkinson disease / Author: Alex
Tags: Disease, parkinsons, Progress, Promise
Parkinson’s disease is a neurodegenerative disease that affects nearly a million people in the United States. The symptoms include tremors, slow movement, muscle rigidity and less facial expression. No cure exists for the disease and current medications become less effective over time. William Langston, CEO and scientific director of the Parkinson’s Institute, discusses stem cell-based research strategies to better understand the disease and to find new therapies. The Parkinson’s Institute has an Early Translation grant from CIRM.
Video Rating: 4 / 5
Parkinsons Disease Causes Symptoms Information With Treatment
Parkinson’s is found all over the world. Exact global figures are not always available, though it is estimated that four million people worldwide have the condition. Parkinson’s disease belongs to a group of conditions called movement disorders. Parkinson’s disease afflicts 1 to 1 1/2 million people in the United States. The disorder occurs in all races but is somewhat more prevalent among Caucasians. People with the disease may have trouble walking, talking or doing simple tasks. Dysfunctional antioxidative mechanisms are associated with older age as well, suggesting that the acceleration of age-related changes in dopamine production may be a factor. Parkinson’s disease patients have at least one relative with parkinsonian symptoms, suggesting that a genetic factor may be involved. There is no cure for Parkinson’s at present, drugs are used to try to control symptoms of Parkinson’s. The most widely used form of treatment is L-dopa in various forms. L-dopa is transformed into dopamine in the dopaminergic neurons by L-aromatic amino acid decarboxylase (often known by its former name dopa-decarboxylase). The most widely practiced treatment for the speech disorders associated with Parkinson’s disease is Lee Silverman Voice Treatment (LSVT). LSVT focuses on increasing vocal loudness. Regular physical exercise and/or therapy can be beneficial to the patient for maintaining and improving mobility, flexibility, balance and a range of motion. Nutrients have been used in clinical studies and are widely used by people with Parkinson’s disease in order to partially treat PD or slow down its deterioration.
Causes of Parkinsons Disease
Common Causes and Risk factors of Parkinsons Disease
Free radicals.
Accelerated aging.
Environmental toxins.
Genetic factors.
Trauma.
Carbon monoxide poisoning.
Hydrocephalus.
Signs and Symptoms of Parkinsons Disease
Common Sign and Symptoms of Parkinsons Disease
Depression and other emotional changes.
Difficulty in swallowing.
Chewing, and speaking.
Urinary problems.
Constipation.
Skin problems.
Sleep disruptions.
Trembling of hands, arms, legs, jaw and face.
Treatment of Parkinsons Disease
Common Treatment of Parkinsons Disease
Successful treatment of Parkinson’s disease involves much more than just the use of drugs. Levodopa and carbidopa combined (Sinemet) is the mainstay of Parkinson’s therapy.
Tolcapone inhibits the COMT enzyme, thereby prolonging the effects of L-dopa, and so has been used to complement L-dopa.
The most widely practiced treatment for the speech disorders associated with Parkinson’s disease is Lee Silverman Voice Treatment (LSVT).
Nutrients have been used in clinical studies and are widely used by people with Parkinson’s disease in order to partially treat PD or slow down its deterioration.
Catechol O-methyl transferase (COMT) inhibitors act by inhibiting catabolism of dopamine, thereby extending L-dopa’s peripheral half-life.
Surgical treatment for PD is generally considered for patients who respond to medications.
Azilect was approved for use as an initial single drug therapy in early Parkinson’s disease. Azilect (rasagiline), a new molecular entity, for the treatment of Parkinson’s disease.
Physical therapy can help strengthen and tone underused muscles, and give rigid muscles a better range of motion.
Juliet Cohen writes articles on diseases and conditions and skin disorders. She also writes articles on herbal home remedies.
Parkinson’s Disease: A Complete Guide for Patients and Families, Second Edition (A Johns Hopkins Press Health Book)
- ISBN13: 9780801885464
- Condition: NEW
- Notes: Brand New from Publisher. No Remainder Mark.
Recent innovations, including deep brain stimulation and new medications, have significantly improved the lives of people with Parkinson’s disease. Nevertheless, medical, emotional, and physical challenges remain. The second edition of this accessible and comprehensive guide provides crucial information for managing this complex condition, including details on the use of medications, diet, exercise, complementary therapies, and surgery. The second edition includes new information about:• The g
Rating: 
(out of 16 reviews)
List Price: $ 17.95
Price: $ 10.17
Question by Bigbird333: How does parkinson disease affect cells of the body?
and what cells of the body does parkinson disease affect?
thanks and NO STUIPID ANSWERS! i need it for a project that is due tommorow!
Best answer:
Answer by Doctor J
Parkinson’s disease results from loss of dopamine producing cells in the part of the brain called the Substantia Nigra.
What do you think? Answer below!
Comments: 17
@yeagers1 The cells used to create reprogrammed stem cells (also called iPS cells) come from skin biopsies. Doctors remove a dime-sized patch of skin in a procedure that takes about 15 minutes.
do yall kill people to try to get this cells ?
a parkinsons patient on their deathbed should donate live cells….there must be patients in coma or otherwise who can help!!!
excellent work!
Playing Wii Sports might help them by haveing them move while having fun.
I really hope they do develop a cure.
I feel terrible for never really noticing this before today. I was reading an article in Scientific American Mind about ADD/ADHD drugs possibly having hidden risks from long term use, the development of Parkinson’s was one thing noticed in research. Of course their research was all from animals and though some may be similar they are not the same as humans. I hope it isn’t true for humans. (I have ADD and take adderall so this worries me a lot)
@MrSymposier
plz forward me stem cells treatment for Parkinson’s disease
im 14 i bet when im 1in 2-3 more years there will be a cure
someone i love dearly has the disease. i believe that poople with tremors should not be embarrased. And i do hope stem cell research is a future possible cure.
I’ve already seen a video about stem cells treatment for Parkinson’s disease, but I did not know that this stem cells could be used to create brain cells from skin cells extracted from a Parkinson’s patients, that technology is really amazing. Other nice videos on Parkinson Disease are available at Symposier site, join our Medical Community and share your videos and Experience with us (Physicians and Medical Experts only).
Frank- your openness and honesty helps us all to understand this disease and hopefully find a cure- soon!
Review by B. J. Emerson for Parkinson’s Disease: A Complete Guide for Patients and Families, Second Edition (A Johns Hopkins Press Health Book)
Rating:
Never having had any experience or knowledge on the basis of this disease, I got the book to help me understand my father’s disease. I have gotten a fuller understanding of the causes of the disease, the symptoms, the treatments (and making decisions regarding the selections of the treatments), and the progression of the disease. I feel much better informed and feel I can support my father better because of it. It was definitely written to help support the patient and family supporting that patient.
Review by Ashley Raczkowski for Parkinson’s Disease: A Complete Guide for Patients and Families, Second Edition (A Johns Hopkins Press Health Book)
Rating:
The author of this book did a great job in explaining what Parkinson’s Disease is and giving information for the patient and the caregiver. I am a dental hygienist and I learned just an overview of the disease in school. After having my first patient with the disease I decided to learn more about it. I learned alot from this book that I should of already known for my patient. The book tells you the symptoms and the side effects of the disease and advice on drug therapy, diet, and exercise. Some people don’t even know that they have the disease for a couple of months or even years. They think it is just old age or arthritis. The book also states what kind of medical advice to seek.
I have never met a patient with Parkinson’s Disease until a couple of months ago. I didn’t know what to expect. When the patient walked in I was shocked. She looked normal and wasn’t shaking. She was the sweetest patient I had met. She explained to me her life and how she lives with the disease. She said that she sometimes gets embarrased to be seen in public when she has her tremors because she thinks that everyone is staring at her. But she said she is the same person as all of us. She just has to take medication and she gets tired alot more than you and me. When I was cleaning her teeth she only had mild tremors so it wasn’t that difficult to work on her. But one day I will probably get a patient who has severe tremors but I am ready thanks to this book in guiding me with the knowledge of what I needed to know. I think that if you know someone who has Parkinson’s disease or if you would like to learn more about the disease buy this book and you will be filled with all the information you need to know about Parkinson’s disease.
Review by Lisa for Parkinson’s Disease: A Complete Guide for Patients and Families, Second Edition (A Johns Hopkins Press Health Book)
Rating:
Very informative. This books explains in PLAIN ENGLISH what the Dr’s look for when making a diagnosis. Also it explains what the average PD. patient goes through in stages. I give it 5 stars!
Review by Jennifer M. Molnar for Parkinson’s Disease: A Complete Guide for Patients and Families, Second Edition (A Johns Hopkins Press Health Book)
Rating:
If you have PD or care for someone or know someone with it you will find this book helpful in any of those situations. I learned many things from this book. Including that some things my husband, who has early onset PD, was going through that turned out were symptoms and not just random events. I thank those that wrote this for helping me care for him and being informed. Also, they section on young onset PD really helped because i was beginning to feel he had intermediate PD when really it was signs and symptoms from his Y.O.P.D. It lifted a heavy weight knowing he wasn’t that far into the disease (intermediate stage). I was able to rely many things to his nuerologist that he was experiencing based upon my reading so he can get better care. Thank you.
Review by Frank Madden for Parkinson’s Disease: A Complete Guide for Patients and Families, Second Edition (A Johns Hopkins Press Health Book)
Rating:
I have Parkinson’s, and this is the most comprehensive, up-to-date book on the subject I’ve seen. If you are buying one book on this topic, this is the book to get.
I have Parkinsons diseade real bad. It affects thebrain.The brain is supposed to make a substance called dopameine,Im not sure Ispelled it correctly. I am online at this time if you would care to chat.