and what cells of the body does parkinson disease affect?
thanks and NO STUIPID ANSWERS! i need it for a project that is due tommorow!

Parkinson Disease Symptoms

Parkinson disease belongs to the group of degenerating diseases that injure the brain, the hub of the central nervous system. The primary symptoms of Parkinson’s disease stem from the deterioration of the part of the brain that controls motor functioning. The primary cause of Parkinson’s disease is still speculative, though most researches believe it’s a combination of genetics and environment. One theory hypothesizes that neuronal deterioration in the brain is caused by the accumulation of free radicals as a result of exposure to toxins possible from food and pesticides.

It’s hard to track when a person with this disease first experienced signs of the disease. Most patients mentioned that they first noticed that something is wrong when one of their limbs was trembling. However, a closer inquiry indicates the subtle signs appeared before. The early signs many patients recalled having before the tremor were lack of blinking, Failure to swing one arm when walking, painful shoulder, discomfort of the neck, and feeling of inner trembling.

In most cases the first symptoms that were impossible to ignore appeared in one side of the body, for example, tremble in one of the limbs. The disease progresses slowly and gradually for a decade or more and than strikes the other limb at the same side of the body. Because of the deterioration in motor functioning most patients use a wheel chair in later stages of the disease.

Other symptoms caused by the decreasing of dosage of dopamine in the brain are involuntary tremors when resting-usually involuntary tremors of the limbs, muscles stiffness (losing the ability to make fast and spontaneous movements), slow voluntary movement, difficulties maintaining balance and stable gait (Stooped posture, a tendency to lean forward) an increased production of saliva (drooling), difficulty swallowing, softness of the voice and slurred speech (caused by lack of muscles control), ansomia- reduced sense of smell(inability to sense certain odors), loss of facial expression or “masking”, depression, anxieties, insomnia-sleep problems, constipation, increased sweating and inability to control urine.

Parkinson Disease Treatment

Parkinson disease is a chronic age related disease (mainly develops in people over the age of 50). The disease that affects the control of muscles causing uncontrolled shivering, tremors, muscles stiffness, speech disorders and unbalanced movement is resulted in the deterioration of certain nerve system. The deterioration is caused by the decrease of dopamine in the area of the brain that controls motor functioning called substantia nigra, when 80% of dopamine is lost the symptoms of the disease appear.  Currently, there is no cure; however, there are ways to control the symptoms and to prevent the disease from escalating at least for considerable period.

As many disease researches believe that the causes for this disease is a combination of both genetic tendencies and environmental stresses causing brain cell death.

The treatment today revolves around controlling the signs and symptoms for a long period as possible whilst minimizing possible side effects. However, even with medication and a close treatment the disease usually progresses after 4-6 years causing motor complications and dyskinesia.( a phenomenon that diminishes the control over voluntary movements) The efficacy of medication changes as the disease changes and progresses .

The treatment available today is medications that help protect the neurons that produce dopamine. They decelerate the cells degeneration rate.  One of the medicine is L-dopa is converted into dopamine crossing the blood-brain barrier. The discovery of this medicine was a real breakthrough; however the main shortcoming of this medicine is that overtime the efficacy wears off and may cause involuntary movement. Another drug therapy is usually used along with L-dopa to make it more effective is the Seligiline that functions an inhibitor of the enzyme monoamine oxidase B which breaks down dopamine. Seligiline is usually given in the early stages of the disease and known to cause fewer side effects than other drugs.

My father have Parkinson disease and I would like to know If there is any cure discovered or something..
Thanks!

my mother’s fingers tremors at rest and we went see a doctor but the doctor said that it has to tremor all the time to be a parkinson disease. but i just don’t feel good watching my mom’s finger tremors at times and not sure what to do to convince the doctor to examine her in more details?
( there was one time i saw her half body tremors while she stars at TV without any emotions…it only happened once but that just scares me and i really fear there is something wrong with her…)
the tremors happens here and there (not all the time) so when we saw the doctor it was not happening and the doctor said that it has to be all the time to be a parkinson…but i checked the internet that seems to say otherwise??? not sure if i understand the internet correctly?

i need to find a parkinson disease exersise dvd for my aunt in germany,as she is not good with the internet,and asked me to fin one for her in england,unfortunately she doesn’t speek english hence im trying to find it in german.thanks

Please answer me in detail about Parkinson disease.