PROJECT: ON/OFF Living & Coping with Young O nset Parkinson’s Disease Directed, produced, filmed, and edited by Tim Costello. THIS IS A SHORT, NON FINAL PRODCUT, USED AS A TEASER USED TO FIND THE FUNDING NEEDED, 000, TO FINISH THE PROJECT (ONE HOUR DOCUMENTARY). FINAL PROJECT WILL DOCUMENT 6 YOUNG ONSET “LIVING” VICE “SUFFERING” FROM PARKINSON’S DISEASE. FILMMAKER: Tim Costello PROJECT IDEA DEVOLOPED BY: TOM BERDINE SPONSOR/FUND SOURCE: TBD FACTS It is estim ated that 1.5 m illion Am ericans are currently diagnosed w ith Parkinson’s disease. 50000 to 60000 more are diagnosed each year. It is believed that 10% of these are under 49, w ith a good m ajority in their late teens, 20′s, 30′s, and 40′s. These individuals are graduating college, starting careers, relationships, families, and trying to build a future for themselves and their loved ones. These are referred to as being diagnosed as “young onset”. ABOUT THE PROJECT The film project is a documentary that will give the audience a front row seat into the normally private lives of six people diagnosed w ith young onset Parkinson’s disease. The film w ill be unscripted, real, at times humorous and other times shocking. It will show them living life as close to or better then before diagnosis. It will show them accommodating these symptoms and side effects despite the daily challenges thrown at them by the symptoms of the disease and side effects of the various medications. Video Rating: 4 / 5
Life With Parkinson’s Disease Chronicled in Self Published Book
The Xlibris release, Calvinâs Journey with Parkinsonâs, chronicles Calvin Broadheadâs life and his efforts to survive Parkinsonâs disease. Author Bonnie McCollough Broadhead brings full attention to her husbandâs story and the degenerative disease that has beset Calvin and people in their twilight years.
Parkinsonâs disease impairs a personâs motor skills, speech and other motor functions due to the degeneration of the central nervous system. The manifestation of this disease can range from movement disorders to high-level cognitive dysfunction to subtle language problems. It is these symptoms and other experiences that Bonnie details in this self-published book.
Calvinâs Journey with Parkinsonâs also highlightâs the title characterâs strength and courage throughout his experience of failing health. It is the Bonnieâs intention to bring wisdom pertaining to Parkinsonâs disease, so others who suffer the illness can learn from similar circumstances that Calvin went through.
Calvinâs Journey with Parkinsonâs is a helpful resource for individuals with Parkinsonâs disease and people who have loved ones who suffer from the illness.
About the Author Bonnie McCollough Broadhead was born December 25, 1928, in Hattiesburg, Mississippi. She was the first born of five children into the family of Amanda Josephine Hensarling McCollough and Myles McCollough. She finished high school and earned two years of college. She married Calvin C. Broadhead in January 1947 and they has two daughters — Carmen Colleen Broadhead Malone and Deborah Amanda Broadhead Houston.
Calvin was diagnosed with Parkinsonâs disease in 1987 shortly after his retirement. He died July 9, 2002. Both their daughters and all three of Bonnie’s brothers are very attentive to her. They take special care of her needs. Bonnie now reside in Madison, Mississippi, with her oldest daughter.
About Xlibris Xlibris was founded in 1997 and, as the leading publishing services provider for authors, has helped to publish more than 20,000 titles. Xlibris is based in Philadelphia, PA and provides authors with direct and personal access to quality publication in hardcover, trade paperback, custom leather-bound, and full-color formats.
For more information, please visit http://www.xlibris.com/requestkit/index.asp?src=apr&key=mm, e-mail pressrelease@xlibris.com or call at 1-888-795-4247, to receive a free publishing guide.
Xlibris is a book publisher founded in 1997 and, as the leading publishing services provider for authors, has helped to publish more than 20,000 titles, and provides authors with direct and personal access to quality publication in hardcover, trade paperback, custom leather-bound, and full-color formats.
Michael J. Fox returning to TV
The veteran actor, who is battling Parkinson’s disease, will appear as Simon Canning, a “shrewd and cynical” lawyer who tackles Margulies’ character in a class action lawsuit, CBS network executives revealed on Friday. Read more on KIMT Mason City
Question by mandy45503: How does late stage Parkinson’s disease effect the caregiver?
I was wondering if anyone could give me some insight as to how late term parkinsons disease would affect the mental mindset of the caregiver. My grandparents have been married for over 40 years, and my grandfather has had Parkinson’s disease for about 13 of them. I know his medical situation is getting worse as he has been in the hospital three times that know of this year. I can’t drive, but several times over the past year, I have made arrangements to visit, only to be told at the last minute that a visit would be inopportune. My grandmother is his primary caregiver and is withdrawing into herself, and I can’t say I blame her, but I am concerned that my son will never get a chance to meet his great grandparents. My grandparents and I have always had a wonderful relationship, but a rather closed one. Is this type of behavior expected in the stressed caregiver? How can I get her to open up about such an off-limits topic? I truly care and would like to know what is going on.Thanks
Best answer:
Answer by life’sgreat This can happen to anyone who has been in your grandmother’s position, esp for that length of time. You say you’ve always had an excellent but closed relationship with your grandparents. In that case, I would talk to your grandmother over the phone and explain your feelings regarding your son. See if you can arrange for someone to sit with your grandfather for a few hours while you and your grandmother and your son have some time together and then try to see your grandfather briefly after that… Also, here’s a website you might find useful.
Since the topic is off-limits, as you say, I’m sure progress will be slow, but if you can be in touch with your grandmother frequently (phone, letter) it would be a start! Good luck
Know better? Leave your own answer in the comments!
PROJECT: ON/OFF Living & Coping with Young O nset Parkinson’s Disease Directed, produced, filmed, and edited by Tim Costello. THIS IS A SHORT, NON FINAL PRODCUT, USED AS A TEASER USED TO FIND THE FUNDING NEEDED, 000, TO FINISH THE PROJECT (ONE HOUR DOCUMENTARY). FINAL PROJECT WILL DOCUMENT 6 YOUNG ONSET “LIVING” VICE “SUFFERING” FROM PARKINSON’S DISEASE. FILMMAKER: Tim Costello PROJECT IDEA DEVOLOPED BY: TOM BERDINE SPONSOR/FUND SOURCE: TBD FACTS It is estim ated that 1.5 m illion Am ericans are currently diagnosed w ith Parkinson’s disease. 50000 to 60000 more are diagnosed each year. It is believed that 10% of these are under 49, w ith a good m ajority in their late teens, 20′s, 30′s, and 40′s. These individuals are graduating college, starting careers, relationships, families, and trying to build a future for themselves and their loved ones. These are referred to as being diagnosed as “young onset”. ABOUT THE PROJECT The film project is a documentary that will give the audience a front row seat into the normally private lives of six people diagnosed w ith young onset Parkinson’s disease. The film w ill be unscripted, real, at times humorous and other times shocking. It will show them living life as close to or better then before diagnosis. It will show them accommodating these symptoms and side effects despite the daily challenges thrown at them by the symptoms of the disease and side effects of the various medications. Video Rating: 4 / 5
The Repercussions of Parkinson’s Disease in Oral Health
An estimated 50,000 Americans are diagnosed with Parkinson’s Disease each year. It generally affects people in their middle to late years. It is a kind of disorder that causes uncontrollable muscle movements, tremors, muscle rigidity and may even lead to severe memory loss. The patient’s speech and motors skills can also suffer.
Parkinson’s Disease is a degenerative disorder that affects the body’s nervous system which in turn is responsible for the relay of communication between the brain and the muscles. A disruption occurs in the nervous system that gravely affects reactions and movements of the muscles leading to such abnormalities as tremors and rigidity.
The disease usually starts to show symptoms with just a few individual muscle tremors. Sometimes it can manifest itself due to lack of muscle controls that are gradually visible to other people. This can be lack of facial expressions, mumbling sounds while talking, and even the non-movement of the arms while walking. These are simple symptoms that may usually mean the starting occurrence of Parkinson’s Disease.
A patient suffering from this disease may likewise suffer from very poor dental hygiene. While it is true that most people who have Parkinson’s Disease are already old and therefore no longer requires a set of perfect teeth, the fact remains that oral health is an important factor on the overall health condition of an individual. Therefore it is of high importance that people suffering from this disease still get the right amount of dental hygiene.
Because of the weakness of the muscles, a patient may not be able to brush his own teeth. As such, he may require the assistance of another person preferably from a well-trained professional like a caregiver. An expert assistance is necessary to make sure that the patient gets the best dental hygiene even for his condition. This may mean brushing the patient’s teeth, flossing them and administering any required medicines.
Another important point to consider is that some Parkinson’s Disease patients are prescribed to take drugs that can cause xerostomia. Xerostomia is more commonly called dry mouth. The saliva is an important component of a good oral hygiene as it helps clean the mouth by fighting off bacteria. Now, a person who suffers from xerostomia has higher risk of developing tooth decay, halitosis and other periodontal diseases and disorders. If you have constant dry mouth, your dentist can prescribe you with a medicine that can stimulate the production of more saliva as well as prescribing you with fluoride treatments to help battle tooth decay.
Also, due to the fact that Parkinson’s Disease patients may suffer from tremors, muscle rigidity and weakness, as well as feel agitated, it will be harder to keep him still in the dentist’s chair. This is very important because it makes it harder for the dentist to conduct the necessary dental procedures. Some form of equipment and contraptions may be used to keep the patient still. For much worse situations, the dentist may require to sedate his patient to avoid any unnecessary movements during the treatment.
If you want to learn more about Parkinsons disease and its implications when it comes to oral health get straight answers from professionals who also provide info on the correlation between Osseous Surgery and dental health, visit us at http://www.cosmeticdentistryguide.co.uk
Parkinson’s disease linked to immune system gene
Researchers found a gene in a region that contains a many of genes related to fighting infections was strongly linked with Parkinson’s disease. Read more on Daily Mail
Question by Courtney: What is the genetic basis for Parkinson’s Disease?
I am currently working on a project for my biology class on parkinson’s disease. in one of the boxes i have to put the genetic basis for PD.
(for example, is it sex linked, controlled by one or multiple alleles, non disjunction, random mutation of a certain gene, etc.)
I can’t seem to find these answers anywhere.
Any answers or suggestions of sites would be great, thanks.
Best answer:
Answer by Mags The jury is still out for the full genetic basis for PD.
The latest concept is that Parkinson’s disease is genetic and can remain dormant for generations. One reason that PD was not thought to be primarily or strictly genetic in nature was that sometimes many generations were skipped. It is possible that other factors have to act as the trigger. Environmental, medications, heavy metal exposure and the like.
I put the best link last but read down first as the expository info will be in the earlier links.
The first link is for two studies completed in 2008 by two researchers from the Mayo clinic where PD studies have been conducted for many years.
In one study a mutation of LRRK2-R1628P has been traced back to 2,500 BC. LRRK2-G2385R has been traced back 4,500 years.
Another study found that LRRK2-R1441C can increase the chances of developing PD by 10X.
http://www.scientistlive.com/European-Sc…
Next let’s go to the LRRK2 (leucine-rich repeat kinease2) autosomal dominant mutation which you can read about here for starters because it has been identified in almost 5% of PD cases:
http://www.thelancet.com/journals/lancet…
There is a study currently recruiting for a LRRK2 study in Maryland:
http://clinicaltrials.gov/ct2/show/NCT00…
Glucocerebrosidase gene
GBA mutations (N370S, L444P, 84GG, IVS+1, V394L, and R496H) that are most common among Ashkenazi Jews
http://www.thelancet.com/journals/laneur…
70117-0/abstract
and GBA-Gly2019SER here:
http://content.nejm.org/cgi/content/shor…
A study published in 2007 indicated that genetic mutations were 2X as common in YOPD (Young or early onset Parkinson’s Disease) and in people of Jewish Ancestry – specifically Ashkenazic)
Here is an abstract link about DJ-1, an autosomal recessive linked to PD. The abstract also references PARK6 and PARK7:
http://jnnp.bmj.com/cgi/content/abstract…
The best gene data base is here – it is a public and you can link to the site to see it:
http://datam.i2r.a-star.edu.sg/mdpd/stat…
In this chart you will see the gene, the number of reports and ethnic groups
Naturally it begins with LRRK2. PARK2 followed by SNCA, CYP2D6, PINK1, MAPT, UCHL1, MAOB, PARK7 and APOE
It then lists the top 10 genes with the most variants followed by the top 10 with the most negative reports.
There are several other comparisons you can do at the site, it is amazing. Check it out.
While it is true that more men than women develop PD that may be because of a bioprotectiveness of estrogen. Which of course ends at sometime with menopause.
You should probably search for Chinese – HAN – gene – Parkinson’s disease. You might find the rest of the answer which you need. There are also several familial studies. I have read the abstracts but not the full studies.
Here are a few which should help:
http://www.ncbi.nlm.nih.gov/pubmed/12730996
Here’s a familial study from Italy but it is older, 2003:
To properly search just enter each term with Parkinson’s disease and you will find a host of abstracts and some articles about the abstracts. You will not find definitive answers because they aren’t there yet. Pd is a complicated disease.
Add your own answer in the comments!
Stretching for the Parkinson’s 5K Walk and Fun Run 2008
PROJECT: ON/OFF Living & Coping with Young O nset Parkinson’s Disease Directed, produced, filmed, and edited by Tim Costello. THIS IS A SHORT, NON FINAL PRODCUT, USED AS A TEASER USED TO FIND THE FUNDING NEEDED, 000, TO FINISH THE PROJECT (ONE HOUR DOCUMENTARY). FINAL PROJECT WILL DOCUMENT 6 YOUNG ONSET “LIVING” VICE “SUFFERING” FROM PARKINSON’S DISEASE. FILMMAKER: Tim Costello PROJECT IDEA DEVOLOPED BY: TOM BERDINE SPONSOR/FUND SOURCE: TBD FACTS It is estim ated that 1.5 m illion Am ericans are currently diagnosed w ith Parkinson’s disease. 50000 to 60000 more are diagnosed each year. It is believed that 10% of these are under 49, w ith a good m ajority in their late teens, 20′s, 30′s, and 40′s. These individuals are graduating college, starting careers, relationships, families, and trying to build a future for themselves and their loved ones. These are referred to as being diagnosed as “young onset”. ABOUT THE PROJECT The film project is a documentary that will give the audience a front row seat into the normally private lives of six people diagnosed w ith young onset Parkinson’s disease. The film w ill be unscripted, real, at times humorous and other times shocking. It will show them living life as close to or better then before diagnosis. It will show them accommodating these symptoms and side effects despite the daily challenges thrown at them by the symptoms of the disease and side effects of the various medications. Video Rating: 4 / 5
The Repercussions of Parkinson’s Disease in Oral Health
An estimated 50,000 Americans are diagnosed with Parkinson’s Disease each year. It generally affects people in their middle to late years. It is a kind of disorder that causes uncontrollable muscle movements, tremors, muscle rigidity and may even lead to severe memory loss. The patient’s speech and motors skills can also suffer.
Parkinson’s Disease is a degenerative disorder that affects the body’s nervous system which in turn is responsible for the relay of communication between the brain and the muscles. A disruption occurs in the nervous system that gravely affects reactions and movements of the muscles leading to such abnormalities as tremors and rigidity.
The disease usually starts to show symptoms with just a few individual muscle tremors. Sometimes it can manifest itself due to lack of muscle controls that are gradually visible to other people. This can be lack of facial expressions, mumbling sounds while talking, and even the non-movement of the arms while walking. These are simple symptoms that may usually mean the starting occurrence of Parkinson’s Disease.
A patient suffering from this disease may likewise suffer from very poor dental hygiene. While it is true that most people who have Parkinson’s Disease are already old and therefore no longer requires a set of perfect teeth, the fact remains that oral health is an important factor on the overall health condition of an individual. Therefore it is of high importance that people suffering from this disease still get the right amount of dental hygiene.
Because of the weakness of the muscles, a patient may not be able to brush his own teeth. As such, he may require the assistance of another person preferably from a well-trained professional like a caregiver. An expert assistance is necessary to make sure that the patient gets the best dental hygiene even for his condition. This may mean brushing the patient’s teeth, flossing them and administering any required medicines.
Another important point to consider is that some Parkinson’s Disease patients are prescribed to take drugs that can cause xerostomia. Xerostomia is more commonly called dry mouth. The saliva is an important component of a good oral hygiene as it helps clean the mouth by fighting off bacteria. Now, a person who suffers from xerostomia has higher risk of developing tooth decay, halitosis and other periodontal diseases and disorders. If you have constant dry mouth, your dentist can prescribe you with a medicine that can stimulate the production of more saliva as well as prescribing you with fluoride treatments to help battle tooth decay.
Also, due to the fact that Parkinson’s Disease patients may suffer from tremors, muscle rigidity and weakness, as well as feel agitated, it will be harder to keep him still in the dentist’s chair. This is very important because it makes it harder for the dentist to conduct the necessary dental procedures. Some form of equipment and contraptions may be used to keep the patient still. For much worse situations, the dentist may require to sedate his patient to avoid any unnecessary movements during the treatment.
If you want to learn more about Parkinsons disease and its implications when it comes to oral health get straight answers from professionals who also provide info on the correlation between Osseous Surgery and dental health, visit us at http://www.cosmeticdentistryguide.co.uk
Parkinson’s disease linked to immune system gene
Researchers found a gene in a region that contains a many of genes related to fighting infections was strongly linked with Parkinson’s disease. Read more on Daily Mail
Question by Courtney: What is the genetic basis for Parkinson’s Disease?
I am currently working on a project for my biology class on parkinson’s disease. in one of the boxes i have to put the genetic basis for PD.
(for example, is it sex linked, controlled by one or multiple alleles, non disjunction, random mutation of a certain gene, etc.)
I can’t seem to find these answers anywhere.
Any answers or suggestions of sites would be great, thanks.
Best answer:
Answer by Mags The jury is still out for the full genetic basis for PD.
The latest concept is that Parkinson’s disease is genetic and can remain dormant for generations. One reason that PD was not thought to be primarily or strictly genetic in nature was that sometimes many generations were skipped. It is possible that other factors have to act as the trigger. Environmental, medications, heavy metal exposure and the like.
I put the best link last but read down first as the expository info will be in the earlier links.
The first link is for two studies completed in 2008 by two researchers from the Mayo clinic where PD studies have been conducted for many years.
In one study a mutation of LRRK2-R1628P has been traced back to 2,500 BC. LRRK2-G2385R has been traced back 4,500 years.
Another study found that LRRK2-R1441C can increase the chances of developing PD by 10X.
http://www.scientistlive.com/European-Sc…
Next let’s go to the LRRK2 (leucine-rich repeat kinease2) autosomal dominant mutation which you can read about here for starters because it has been identified in almost 5% of PD cases:
http://www.thelancet.com/journals/lancet…
There is a study currently recruiting for a LRRK2 study in Maryland:
http://clinicaltrials.gov/ct2/show/NCT00…
Glucocerebrosidase gene
GBA mutations (N370S, L444P, 84GG, IVS+1, V394L, and R496H) that are most common among Ashkenazi Jews
http://www.thelancet.com/journals/laneur…
70117-0/abstract
and GBA-Gly2019SER here:
http://content.nejm.org/cgi/content/shor…
A study published in 2007 indicated that genetic mutations were 2X as common in YOPD (Young or early onset Parkinson’s Disease) and in people of Jewish Ancestry – specifically Ashkenazic)
Here is an abstract link about DJ-1, an autosomal recessive linked to PD. The abstract also references PARK6 and PARK7:
http://jnnp.bmj.com/cgi/content/abstract…
The best gene data base is here – it is a public and you can link to the site to see it:
http://datam.i2r.a-star.edu.sg/mdpd/stat…
In this chart you will see the gene, the number of reports and ethnic groups
Naturally it begins with LRRK2. PARK2 followed by SNCA, CYP2D6, PINK1, MAPT, UCHL1, MAOB, PARK7 and APOE
It then lists the top 10 genes with the most variants followed by the top 10 with the most negative reports.
There are several other comparisons you can do at the site, it is amazing. Check it out.
While it is true that more men than women develop PD that may be because of a bioprotectiveness of estrogen. Which of course ends at sometime with menopause.
You should probably search for Chinese – HAN – gene – Parkinson’s disease. You might find the rest of the answer which you need. There are also several familial studies. I have read the abstracts but not the full studies.
Here are a few which should help:
http://www.ncbi.nlm.nih.gov/pubmed/12730996
Here’s a familial study from Italy but it is older, 2003:
To properly search just enter each term with Parkinson’s disease and you will find a host of abstracts and some articles about the abstracts. You will not find definitive answers because they aren’t there yet. Pd is a complicated disease.
Add your own answer in the comments!
Stretching for the Parkinson’s 5K Walk and Fun Run 2008
PROJECT: ON/OFF Living & Coping with Young O nset Parkinson’s Disease Directed, produced, filmed, and edited by Tim Costello. THIS IS A SHORT, NON FINAL PRODCUT, USED AS A TEASER USED TO FIND THE FUNDING NEEDED, 000, TO FINISH THE PROJECT (ONE HOUR DOCUMENTARY). FINAL PROJECT WILL DOCUMENT 6 YOUNG ONSET “LIVING” VICE “SUFFERING” FROM PARKINSON’S DISEASE. FILMMAKER: Tim Costello PROJECT IDEA DEVOLOPED BY: TOM BERDINE SPONSOR/FUND SOURCE: TBD FACTS It is estim ated that 1.5 m illion Am ericans are currently diagnosed w ith Parkinson’s disease. 50000 to 60000 more are diagnosed each year. It is believed that 10% of these are under 49, w ith a good m ajority in their late teens, 20′s, 30′s, and 40′s. These individuals are graduating college, starting careers, relationships, families, and trying to build a future for themselves and their loved ones. These are referred to as being diagnosed as “young onset”. ABOUT THE PROJECT The film project is a documentary that will give the audience a front row seat into the normally private lives of six people diagnosed w ith young onset Parkinson’s disease. The film w ill be unscripted, real, at times humorous and other times shocking. It will show them living life as close to or better then before diagnosis. It will show them accommodating these symptoms and side effects despite the daily challenges thrown at them by the symptoms of the disease and side effects of the various medications.
The Repercussions of Parkinson’s Disease in Oral Health
An estimated 50,000 Americans are diagnosed with Parkinson’s Disease each year. It generally affects people in their middle to late years. It is a kind of disorder that causes uncontrollable muscle movements, tremors, muscle rigidity and may even lead to severe memory loss. The patient’s speech and motors skills can also suffer.
Parkinson’s Disease is a degenerative disorder that affects the body’s nervous system which in turn is responsible for the relay of communication between the brain and the muscles. A disruption occurs in the nervous system that gravely affects reactions and movements of the muscles leading to such abnormalities as tremors and rigidity.
The disease usually starts to show symptoms with just a few individual muscle tremors. Sometimes it can manifest itself due to lack of muscle controls that are gradually visible to other people. This can be lack of facial expressions, mumbling sounds while talking, and even the non-movement of the arms while walking. These are simple symptoms that may usually mean the starting occurrence of Parkinson’s Disease.
A patient suffering from this disease may likewise suffer from very poor dental hygiene. While it is true that most people who have Parkinson’s Disease are already old and therefore no longer requires a set of perfect teeth, the fact remains that oral health is an important factor on the overall health condition of an individual. Therefore it is of high importance that people suffering from this disease still get the right amount of dental hygiene.
Because of the weakness of the muscles, a patient may not be able to brush his own teeth. As such, he may require the assistance of another person preferably from a well-trained professional like a caregiver. An expert assistance is necessary to make sure that the patient gets the best dental hygiene even for his condition. This may mean brushing the patient’s teeth, flossing them and administering any required medicines.
Another important point to consider is that some Parkinson’s Disease patients are prescribed to take drugs that can cause xerostomia. Xerostomia is more commonly called dry mouth. The saliva is an important component of a good oral hygiene as it helps clean the mouth by fighting off bacteria. Now, a person who suffers from xerostomia has higher risk of developing tooth decay, halitosis and other periodontal diseases and disorders. If you have constant dry mouth, your dentist can prescribe you with a medicine that can stimulate the production of more saliva as well as prescribing you with fluoride treatments to help battle tooth decay.
Also, due to the fact that Parkinson’s Disease patients may suffer from tremors, muscle rigidity and weakness, as well as feel agitated, it will be harder to keep him still in the dentist’s chair. This is very important because it makes it harder for the dentist to conduct the necessary dental procedures. Some form of equipment and contraptions may be used to keep the patient still. For much worse situations, the dentist may require to sedate his patient to avoid any unnecessary movements during the treatment.
If you want to learn more about Parkinsons disease and its implications when it comes to oral health get straight answers from professionals who also provide info on the correlation between Osseous Surgery and dental health, visit us at http://www.cosmeticdentistryguide.co.uk
Michael J. Fox Shows us Anything is Possible
Michael J. Fox is well known for his role on various hit TV shows and movies such as “Family Ties” or “Back to the Future. Fox may be equally known for his battle with Parkinson’s Disease. Fox was diagnosed with Parkinson’s Disease in 1991, and disclosed his condition to the public in 1998. He semi-retired from acting in 2000 as the symptoms of his disease worsened. He has since become an … Read more on ThirdAge
Question by The Unpublished Poet: Why do people think that those with movement disorders like Parkinson’s Disease are faking it to get attention?
I think I have something similar to familial PKD (which is similar to Parkinson’s Disease, except sporadic).
However, there are people who think that people with movement disorders are faking it to get attention.
Why do they think that?
Best answer:
Answer by Croatian ♠ Angel ignorance…just try and don’t let them get to you
What do you think? Answer below!
Stretching for the Parkinson’s 5K Walk and Fun Run 2008
PROJECT: ON/OFF Living & Coping with Young O nset Parkinson’s Disease Directed, produced, filmed, and edited by Tim Costello. THIS IS A SHORT, NON FINAL PRODCUT, USED AS A TEASER USED TO FIND THE FUNDING NEEDED, 000, TO FINISH THE PROJECT (ONE HOUR DOCUMENTARY). FINAL PROJECT WILL DOCUMENT 6 YOUNG ONSET “LIVING” VICE “SUFFERING” FROM PARKINSON’S DISEASE. FILMMAKER: Tim Costello PROJECT IDEA DEVOLOPED BY: TOM BERDINE SPONSOR/FUND SOURCE: TBD FACTS It is estim ated that 1.5 m illion Am ericans are currently diagnosed w ith Parkinson’s disease. 50000 to 60000 more are diagnosed each year. It is believed that 10% of these are under 49, w ith a good m ajority in their late teens, 20′s, 30′s, and 40′s. These individuals are graduating college, starting careers, relationships, families, and trying to build a future for themselves and their loved ones. These are referred to as being diagnosed as “young onset”. ABOUT THE PROJECT The film project is a documentary that will give the audience a front row seat into the normally private lives of six people diagnosed w ith young onset Parkinson’s disease. The film w ill be unscripted, real, at times humorous and other times shocking. It will show them living life as close to or better then before diagnosis. It will show them accommodating these symptoms and side effects despite the daily challenges thrown at them by the symptoms of the disease and side effects of the various medications. Video Rating: 4 / 5
The Repercussions of Parkinson’s Disease in Oral Health
An estimated 50,000 Americans are diagnosed with Parkinson’s Disease each year. It generally affects people in their middle to late years. It is a kind of disorder that causes uncontrollable muscle movements, tremors, muscle rigidity and may even lead to severe memory loss. The patient’s speech and motors skills can also suffer.
Parkinson’s Disease is a degenerative disorder that affects the body’s nervous system which in turn is responsible for the relay of communication between the brain and the muscles. A disruption occurs in the nervous system that gravely affects reactions and movements of the muscles leading to such abnormalities as tremors and rigidity.
The disease usually starts to show symptoms with just a few individual muscle tremors. Sometimes it can manifest itself due to lack of muscle controls that are gradually visible to other people. This can be lack of facial expressions, mumbling sounds while talking, and even the non-movement of the arms while walking. These are simple symptoms that may usually mean the starting occurrence of Parkinson’s Disease.
A patient suffering from this disease may likewise suffer from very poor dental hygiene. While it is true that most people who have Parkinson’s Disease are already old and therefore no longer requires a set of perfect teeth, the fact remains that oral health is an important factor on the overall health condition of an individual. Therefore it is of high importance that people suffering from this disease still get the right amount of dental hygiene.
Because of the weakness of the muscles, a patient may not be able to brush his own teeth. As such, he may require the assistance of another person preferably from a well-trained professional like a caregiver. An expert assistance is necessary to make sure that the patient gets the best dental hygiene even for his condition. This may mean brushing the patient’s teeth, flossing them and administering any required medicines.
Another important point to consider is that some Parkinson’s Disease patients are prescribed to take drugs that can cause xerostomia. Xerostomia is more commonly called dry mouth. The saliva is an important component of a good oral hygiene as it helps clean the mouth by fighting off bacteria. Now, a person who suffers from xerostomia has higher risk of developing tooth decay, halitosis and other periodontal diseases and disorders. If you have constant dry mouth, your dentist can prescribe you with a medicine that can stimulate the production of more saliva as well as prescribing you with fluoride treatments to help battle tooth decay.
Also, due to the fact that Parkinson’s Disease patients may suffer from tremors, muscle rigidity and weakness, as well as feel agitated, it will be harder to keep him still in the dentist’s chair. This is very important because it makes it harder for the dentist to conduct the necessary dental procedures. Some form of equipment and contraptions may be used to keep the patient still. For much worse situations, the dentist may require to sedate his patient to avoid any unnecessary movements during the treatment.
If you want to learn more about Parkinsons disease and its implications when it comes to oral health get straight answers from professionals who also provide info on the correlation between Osseous Surgery and dental health, visit us at http://www.cosmeticdentistryguide.co.uk
Adult stem cells succeed for lethal disease
WASHINGTON (BP)–University of Minnesota researchers have used non-embryonic stem cells to treat successfully children with a lethal skin disease. Read more on BPNews.net
Question by Courtney: What is the genetic basis for Parkinson’s Disease?
I am currently working on a project for my biology class on parkinson’s disease. in one of the boxes i have to put the genetic basis for PD.
(for example, is it sex linked, controlled by one or multiple alleles, non disjunction, random mutation of a certain gene, etc.)
I can’t seem to find these answers anywhere.
Any answers or suggestions of sites would be great, thanks.
Best answer:
Answer by Mags The jury is still out for the full genetic basis for PD.
The latest concept is that Parkinson’s disease is genetic and can remain dormant for generations. One reason that PD was not thought to be primarily or strictly genetic in nature was that sometimes many generations were skipped. It is possible that other factors have to act as the trigger. Environmental, medications, heavy metal exposure and the like.
I put the best link last but read down first as the expository info will be in the earlier links.
The first link is for two studies completed in 2008 by two researchers from the Mayo clinic where PD studies have been conducted for many years.
In one study a mutation of LRRK2-R1628P has been traced back to 2,500 BC. LRRK2-G2385R has been traced back 4,500 years.
Another study found that LRRK2-R1441C can increase the chances of developing PD by 10X.
http://www.scientistlive.com/European-Sc…
Next let’s go to the LRRK2 (leucine-rich repeat kinease2) autosomal dominant mutation which you can read about here for starters because it has been identified in almost 5% of PD cases:
http://www.thelancet.com/journals/lancet…
There is a study currently recruiting for a LRRK2 study in Maryland:
http://clinicaltrials.gov/ct2/show/NCT00…
Glucocerebrosidase gene
GBA mutations (N370S, L444P, 84GG, IVS+1, V394L, and R496H) that are most common among Ashkenazi Jews
http://www.thelancet.com/journals/laneur…
70117-0/abstract
and GBA-Gly2019SER here:
http://content.nejm.org/cgi/content/shor…
A study published in 2007 indicated that genetic mutations were 2X as common in YOPD (Young or early onset Parkinson’s Disease) and in people of Jewish Ancestry – specifically Ashkenazic)
Here is an abstract link about DJ-1, an autosomal recessive linked to PD. The abstract also references PARK6 and PARK7:
http://jnnp.bmj.com/cgi/content/abstract…
The best gene data base is here – it is a public and you can link to the site to see it:
http://datam.i2r.a-star.edu.sg/mdpd/stat…
In this chart you will see the gene, the number of reports and ethnic groups
Naturally it begins with LRRK2. PARK2 followed by SNCA, CYP2D6, PINK1, MAPT, UCHL1, MAOB, PARK7 and APOE
It then lists the top 10 genes with the most variants followed by the top 10 with the most negative reports.
There are several other comparisons you can do at the site, it is amazing. Check it out.
While it is true that more men than women develop PD that may be because of a bioprotectiveness of estrogen. Which of course ends at sometime with menopause.
You should probably search for Chinese – HAN – gene – Parkinson’s disease. You might find the rest of the answer which you need. There are also several familial studies. I have read the abstracts but not the full studies.
Here are a few which should help:
http://www.ncbi.nlm.nih.gov/pubmed/12730996
Here’s a familial study from Italy but it is older, 2003:
To properly search just enter each term with Parkinson’s disease and you will find a host of abstracts and some articles about the abstracts. You will not find definitive answers because they aren’t there yet. Pd is a complicated disease.
Add your own answer in the comments!
Stretching for the Parkinson’s 5K Walk and Fun Run 2008
PROJECT: ON/OFF Living & Coping with Young O nset Parkinson’s Disease Directed, produced, filmed, and edited by Tim Costello. THIS IS A SHORT, NON FINAL PRODCUT, USED AS A TEASER USED TO FIND THE FUNDING NEEDED, 000, TO FINISH THE PROJECT (ONE HOUR DOCUMENTARY). FINAL PROJECT WILL DOCUMENT 6 YOUNG ONSET “LIVING” VICE “SUFFERING” FROM PARKINSON’S DISEASE. FILMMAKER: Tim Costello PROJECT IDEA DEVOLOPED BY: TOM BERDINE SPONSOR/FUND SOURCE: TBD FACTS It is estim ated that 1.5 m illion Am ericans are currently diagnosed w ith Parkinson’s disease. 50000 to 60000 more are diagnosed each year. It is believed that 10% of these are under 49, w ith a good m ajority in their late teens, 20′s, 30′s, and 40′s. These individuals are graduating college, starting careers, relationships, families, and trying to build a future for themselves and their loved ones. These are referred to as being diagnosed as “young onset”. ABOUT THE PROJECT The film project is a documentary that will give the audience a front row seat into the normally private lives of six people diagnosed w ith young onset Parkinson’s disease. The film w ill be unscripted, real, at times humorous and other times shocking. It will show them living life as close to or better then before diagnosis. It will show them accommodating these symptoms and side effects despite the daily challenges thrown at them by the symptoms of the disease and side effects of the various medications.
The Repercussions of Parkinson’s Disease in Oral Health
An estimated 50,000 Americans are diagnosed with Parkinson’s Disease each year. It generally affects people in their middle to late years. It is a kind of disorder that causes uncontrollable muscle movements, tremors, muscle rigidity and may even lead to severe memory loss. The patient’s speech and motors skills can also suffer.
Parkinson’s Disease is a degenerative disorder that affects the body’s nervous system which in turn is responsible for the relay of communication between the brain and the muscles. A disruption occurs in the nervous system that gravely affects reactions and movements of the muscles leading to such abnormalities as tremors and rigidity.
The disease usually starts to show symptoms with just a few individual muscle tremors. Sometimes it can manifest itself due to lack of muscle controls that are gradually visible to other people. This can be lack of facial expressions, mumbling sounds while talking, and even the non-movement of the arms while walking. These are simple symptoms that may usually mean the starting occurrence of Parkinson’s Disease.
A patient suffering from this disease may likewise suffer from very poor dental hygiene. While it is true that most people who have Parkinson’s Disease are already old and therefore no longer requires a set of perfect teeth, the fact remains that oral health is an important factor on the overall health condition of an individual. Therefore it is of high importance that people suffering from this disease still get the right amount of dental hygiene.
Because of the weakness of the muscles, a patient may not be able to brush his own teeth. As such, he may require the assistance of another person preferably from a well-trained professional like a caregiver. An expert assistance is necessary to make sure that the patient gets the best dental hygiene even for his condition. This may mean brushing the patient’s teeth, flossing them and administering any required medicines.
Another important point to consider is that some Parkinson’s Disease patients are prescribed to take drugs that can cause xerostomia. Xerostomia is more commonly called dry mouth. The saliva is an important component of a good oral hygiene as it helps clean the mouth by fighting off bacteria. Now, a person who suffers from xerostomia has higher risk of developing tooth decay, halitosis and other periodontal diseases and disorders. If you have constant dry mouth, your dentist can prescribe you with a medicine that can stimulate the production of more saliva as well as prescribing you with fluoride treatments to help battle tooth decay.
Also, due to the fact that Parkinson’s Disease patients may suffer from tremors, muscle rigidity and weakness, as well as feel agitated, it will be harder to keep him still in the dentist’s chair. This is very important because it makes it harder for the dentist to conduct the necessary dental procedures. Some form of equipment and contraptions may be used to keep the patient still. For much worse situations, the dentist may require to sedate his patient to avoid any unnecessary movements during the treatment.
If you want to learn more about Parkinsons disease and its implications when it comes to oral health get straight answers from professionals who also provide info on the correlation between Osseous Surgery and dental health, visit us at http://www.cosmeticdentistryguide.co.uk
Stem Cells Successfully Used to Treat Parkinson’s in Rats
Human induced pluripotent stem cells “hot” topic among researchers focused on regenerative medicine. Read more on AnandTech
Question by Courtney: What is the genetic basis for Parkinson’s Disease?
I am currently working on a project for my biology class on parkinson’s disease. in one of the boxes i have to put the genetic basis for PD.
(for example, is it sex linked, controlled by one or multiple alleles, non disjunction, random mutation of a certain gene, etc.)
I can’t seem to find these answers anywhere.
Any answers or suggestions of sites would be great, thanks.
Best answer:
Answer by Mags The jury is still out for the full genetic basis for PD.
The latest concept is that Parkinson’s disease is genetic and can remain dormant for generations. One reason that PD was not thought to be primarily or strictly genetic in nature was that sometimes many generations were skipped. It is possible that other factors have to act as the trigger. Environmental, medications, heavy metal exposure and the like.
I put the best link last but read down first as the expository info will be in the earlier links.
The first link is for two studies completed in 2008 by two researchers from the Mayo clinic where PD studies have been conducted for many years.
In one study a mutation of LRRK2-R1628P has been traced back to 2,500 BC. LRRK2-G2385R has been traced back 4,500 years.
Another study found that LRRK2-R1441C can increase the chances of developing PD by 10X.
http://www.scientistlive.com/European-Sc…
Next let’s go to the LRRK2 (leucine-rich repeat kinease2) autosomal dominant mutation which you can read about here for starters because it has been identified in almost 5% of PD cases:
http://www.thelancet.com/journals/lancet…
There is a study currently recruiting for a LRRK2 study in Maryland:
http://clinicaltrials.gov/ct2/show/NCT00…
Glucocerebrosidase gene
GBA mutations (N370S, L444P, 84GG, IVS+1, V394L, and R496H) that are most common among Ashkenazi Jews
http://www.thelancet.com/journals/laneur…
70117-0/abstract
and GBA-Gly2019SER here:
http://content.nejm.org/cgi/content/shor…
A study published in 2007 indicated that genetic mutations were 2X as common in YOPD (Young or early onset Parkinson’s Disease) and in people of Jewish Ancestry – specifically Ashkenazic)
Here is an abstract link about DJ-1, an autosomal recessive linked to PD. The abstract also references PARK6 and PARK7:
http://jnnp.bmj.com/cgi/content/abstract…
The best gene data base is here – it is a public and you can link to the site to see it:
http://datam.i2r.a-star.edu.sg/mdpd/stat…
In this chart you will see the gene, the number of reports and ethnic groups
Naturally it begins with LRRK2. PARK2 followed by SNCA, CYP2D6, PINK1, MAPT, UCHL1, MAOB, PARK7 and APOE
It then lists the top 10 genes with the most variants followed by the top 10 with the most negative reports.
There are several other comparisons you can do at the site, it is amazing. Check it out.
While it is true that more men than women develop PD that may be because of a bioprotectiveness of estrogen. Which of course ends at sometime with menopause.
You should probably search for Chinese – HAN – gene – Parkinson’s disease. You might find the rest of the answer which you need. There are also several familial studies. I have read the abstracts but not the full studies.
Here are a few which should help:
http://www.ncbi.nlm.nih.gov/pubmed/12730996
Here’s a familial study from Italy but it is older, 2003:
To properly search just enter each term with Parkinson’s disease and you will find a host of abstracts and some articles about the abstracts. You will not find definitive answers because they aren’t there yet. Pd is a complicated disease.
Know better? Leave your own answer in the comments!
Stretching for the Parkinson’s 5K Walk and Fun Run 2008
PROJECT: ON/OFF Living & Coping with Young O nset Parkinson’s Disease Directed, produced, filmed, and edited by Tim Costello. THIS IS A SHORT, NON FINAL PRODCUT, USED AS A TEASER USED TO FIND THE FUNDING NEEDED, 000, TO FINISH THE PROJECT (ONE HOUR DOCUMENTARY). FINAL PROJECT WILL DOCUMENT 6 YOUNG ONSET “LIVING” VICE “SUFFERING” FROM PARKINSON’S DISEASE. FILMMAKER: Tim Costello PROJECT IDEA DEVOLOPED BY: TOM BERDINE SPONSOR/FUND SOURCE: TBD FACTS It is estim ated that 1.5 m illion Am ericans are currently diagnosed w ith Parkinson’s disease. 50000 to 60000 more are diagnosed each year. It is believed that 10% of these are under 49, w ith a good m ajority in their late teens, 20′s, 30′s, and 40′s. These individuals are graduating college, starting careers, relationships, families, and trying to build a future for themselves and their loved ones. These are referred to as being diagnosed as “young onset”. ABOUT THE PROJECT The film project is a documentary that will give the audience a front row seat into the normally private lives of six people diagnosed w ith young onset Parkinson’s disease. The film w ill be unscripted, real, at times humorous and other times shocking. It will show them living life as close to or better then before diagnosis. It will show them accommodating these symptoms and side effects despite the daily challenges thrown at them by the symptoms of the disease and side effects of the various medications.
The Repercussions of Parkinson’s Disease in Oral Health
An estimated 50,000 Americans are diagnosed with Parkinson’s Disease each year. It generally affects people in their middle to late years. It is a kind of disorder that causes uncontrollable muscle movements, tremors, muscle rigidity and may even lead to severe memory loss. The patient’s speech and motors skills can also suffer.
Parkinson’s Disease is a degenerative disorder that affects the body’s nervous system which in turn is responsible for the relay of communication between the brain and the muscles. A disruption occurs in the nervous system that gravely affects reactions and movements of the muscles leading to such abnormalities as tremors and rigidity.
The disease usually starts to show symptoms with just a few individual muscle tremors. Sometimes it can manifest itself due to lack of muscle controls that are gradually visible to other people. This can be lack of facial expressions, mumbling sounds while talking, and even the non-movement of the arms while walking. These are simple symptoms that may usually mean the starting occurrence of Parkinson’s Disease.
A patient suffering from this disease may likewise suffer from very poor dental hygiene. While it is true that most people who have Parkinson’s Disease are already old and therefore no longer requires a set of perfect teeth, the fact remains that oral health is an important factor on the overall health condition of an individual. Therefore it is of high importance that people suffering from this disease still get the right amount of dental hygiene.
Because of the weakness of the muscles, a patient may not be able to brush his own teeth. As such, he may require the assistance of another person preferably from a well-trained professional like a caregiver. An expert assistance is necessary to make sure that the patient gets the best dental hygiene even for his condition. This may mean brushing the patient’s teeth, flossing them and administering any required medicines.
Another important point to consider is that some Parkinson’s Disease patients are prescribed to take drugs that can cause xerostomia. Xerostomia is more commonly called dry mouth. The saliva is an important component of a good oral hygiene as it helps clean the mouth by fighting off bacteria. Now, a person who suffers from xerostomia has higher risk of developing tooth decay, halitosis and other periodontal diseases and disorders. If you have constant dry mouth, your dentist can prescribe you with a medicine that can stimulate the production of more saliva as well as prescribing you with fluoride treatments to help battle tooth decay.
Also, due to the fact that Parkinson’s Disease patients may suffer from tremors, muscle rigidity and weakness, as well as feel agitated, it will be harder to keep him still in the dentist’s chair. This is very important because it makes it harder for the dentist to conduct the necessary dental procedures. Some form of equipment and contraptions may be used to keep the patient still. For much worse situations, the dentist may require to sedate his patient to avoid any unnecessary movements during the treatment.
If you want to learn more about Parkinsons disease and its implications when it comes to oral health get straight answers from professionals who also provide info on the correlation between Osseous Surgery and dental health, visit us at http://www.cosmeticdentistryguide.co.uk
David Zid, an ACE, APG certified trainer, has collaborated with orthopedic surgeon, Thomas H. Mallory, M.D., who is afflicted with Parkinson’s disease, in the development of a Parkinson’s specific fitness program designed to proactively minimize tremors and improve flexibility, stability, balance and strength. Zid demonstrates each move and provides recommendations for exercise frequency, modification and how to adjust the workout as one improves. Parkinson’s patients participating in Zid’s firn
Rating: (out of 3 reviews)
List Price: $ 24.95
Price: $ 24.95
Stem Cells Successfully Used to Treat Parkinson’s in Rats
Human induced pluripotent stem cells “hot” topic among researchers focused on regenerative medicine. Read more on AnandTech
Question by Courtney: What is the genetic basis for Parkinson’s Disease?
I am currently working on a project for my biology class on parkinson’s disease. in one of the boxes i have to put the genetic basis for PD.
(for example, is it sex linked, controlled by one or multiple alleles, non disjunction, random mutation of a certain gene, etc.)
I can’t seem to find these answers anywhere.
Any answers or suggestions of sites would be great, thanks.
Best answer:
Answer by Mags The jury is still out for the full genetic basis for PD.
The latest concept is that Parkinson’s disease is genetic and can remain dormant for generations. One reason that PD was not thought to be primarily or strictly genetic in nature was that sometimes many generations were skipped. It is possible that other factors have to act as the trigger. Environmental, medications, heavy metal exposure and the like.
I put the best link last but read down first as the expository info will be in the earlier links.
The first link is for two studies completed in 2008 by two researchers from the Mayo clinic where PD studies have been conducted for many years.
In one study a mutation of LRRK2-R1628P has been traced back to 2,500 BC. LRRK2-G2385R has been traced back 4,500 years.
Another study found that LRRK2-R1441C can increase the chances of developing PD by 10X.
http://www.scientistlive.com/European-Sc…
Next let’s go to the LRRK2 (leucine-rich repeat kinease2) autosomal dominant mutation which you can read about here for starters because it has been identified in almost 5% of PD cases:
http://www.thelancet.com/journals/lancet…
There is a study currently recruiting for a LRRK2 study in Maryland:
http://clinicaltrials.gov/ct2/show/NCT00…
Glucocerebrosidase gene
GBA mutations (N370S, L444P, 84GG, IVS+1, V394L, and R496H) that are most common among Ashkenazi Jews
http://www.thelancet.com/journals/laneur…
70117-0/abstract
and GBA-Gly2019SER here:
http://content.nejm.org/cgi/content/shor…
A study published in 2007 indicated that genetic mutations were 2X as common in YOPD (Young or early onset Parkinson’s Disease) and in people of Jewish Ancestry – specifically Ashkenazic)
Here is an abstract link about DJ-1, an autosomal recessive linked to PD. The abstract also references PARK6 and PARK7:
http://jnnp.bmj.com/cgi/content/abstract…
The best gene data base is here – it is a public and you can link to the site to see it:
http://datam.i2r.a-star.edu.sg/mdpd/stat…
In this chart you will see the gene, the number of reports and ethnic groups
Naturally it begins with LRRK2. PARK2 followed by SNCA, CYP2D6, PINK1, MAPT, UCHL1, MAOB, PARK7 and APOE
It then lists the top 10 genes with the most variants followed by the top 10 with the most negative reports.
There are several other comparisons you can do at the site, it is amazing. Check it out.
While it is true that more men than women develop PD that may be because of a bioprotectiveness of estrogen. Which of course ends at sometime with menopause.
You should probably search for Chinese – HAN – gene – Parkinson’s disease. You might find the rest of the answer which you need. There are also several familial studies. I have read the abstracts but not the full studies.
Here are a few which should help:
http://www.ncbi.nlm.nih.gov/pubmed/12730996
Here’s a familial study from Italy but it is older, 2003:
To properly search just enter each term with Parkinson’s disease and you will find a host of abstracts and some articles about the abstracts. You will not find definitive answers because they aren’t there yet. Pd is a complicated disease.
What do you think? Answer below!
Stretching for the Parkinson’s 5K Walk and Fun Run 2008
PROJECT: ON/OFF Living & Coping with Young O nset Parkinson’s Disease Directed, produced, filmed, and edited by Tim Costello. THIS IS A SHORT, NON FINAL PRODCUT, USED AS A TEASER USED TO FIND THE FUNDING NEEDED, 000, TO FINISH THE PROJECT (ONE HOUR DOCUMENTARY). FINAL PROJECT WILL DOCUMENT 6 YOUNG ONSET “LIVING” VICE “SUFFERING” FROM PARKINSON’S DISEASE. FILMMAKER: Tim Costello PROJECT IDEA DEVOLOPED BY: TOM BERDINE SPONSOR/FUND SOURCE: TBD FACTS It is estim ated that 1.5 m illion Am ericans are currently diagnosed w ith Parkinson’s disease. 50000 to 60000 more are diagnosed each year. It is believed that 10% of these are under 49, w ith a good m ajority in their late teens, 20′s, 30′s, and 40′s. These individuals are graduating college, starting careers, relationships, families, and trying to build a future for themselves and their loved ones. These are referred to as being diagnosed as “young onset”. ABOUT THE PROJECT The film project is a documentary that will give the audience a front row seat into the normally private lives of six people diagnosed w ith young onset Parkinson’s disease. The film w ill be unscripted, real, at times humorous and other times shocking. It will show them living life as close to or better then before diagnosis. It will show them accommodating these symptoms and side effects despite the daily challenges thrown at them by the symptoms of the disease and side effects of the various medications.
The Repercussions of Parkinson’s Disease in Oral Health
An estimated 50,000 Americans are diagnosed with Parkinson’s Disease each year. It generally affects people in their middle to late years. It is a kind of disorder that causes uncontrollable muscle movements, tremors, muscle rigidity and may even lead to severe memory loss. The patient’s speech and motors skills can also suffer.
Parkinson’s Disease is a degenerative disorder that affects the body’s nervous system which in turn is responsible for the relay of communication between the brain and the muscles. A disruption occurs in the nervous system that gravely affects reactions and movements of the muscles leading to such abnormalities as tremors and rigidity.
The disease usually starts to show symptoms with just a few individual muscle tremors. Sometimes it can manifest itself due to lack of muscle controls that are gradually visible to other people. This can be lack of facial expressions, mumbling sounds while talking, and even the non-movement of the arms while walking. These are simple symptoms that may usually mean the starting occurrence of Parkinson’s Disease.
A patient suffering from this disease may likewise suffer from very poor dental hygiene. While it is true that most people who have Parkinson’s Disease are already old and therefore no longer requires a set of perfect teeth, the fact remains that oral health is an important factor on the overall health condition of an individual. Therefore it is of high importance that people suffering from this disease still get the right amount of dental hygiene.
Because of the weakness of the muscles, a patient may not be able to brush his own teeth. As such, he may require the assistance of another person preferably from a well-trained professional like a caregiver. An expert assistance is necessary to make sure that the patient gets the best dental hygiene even for his condition. This may mean brushing the patient’s teeth, flossing them and administering any required medicines.
Another important point to consider is that some Parkinson’s Disease patients are prescribed to take drugs that can cause xerostomia. Xerostomia is more commonly called dry mouth. The saliva is an important component of a good oral hygiene as it helps clean the mouth by fighting off bacteria. Now, a person who suffers from xerostomia has higher risk of developing tooth decay, halitosis and other periodontal diseases and disorders. If you have constant dry mouth, your dentist can prescribe you with a medicine that can stimulate the production of more saliva as well as prescribing you with fluoride treatments to help battle tooth decay.
Also, due to the fact that Parkinson’s Disease patients may suffer from tremors, muscle rigidity and weakness, as well as feel agitated, it will be harder to keep him still in the dentist’s chair. This is very important because it makes it harder for the dentist to conduct the necessary dental procedures. Some form of equipment and contraptions may be used to keep the patient still. For much worse situations, the dentist may require to sedate his patient to avoid any unnecessary movements during the treatment.
If you want to learn more about Parkinsons disease and its implications when it comes to oral health get straight answers from professionals who also provide info on the correlation between Osseous Surgery and dental health, visit us at http://www.cosmeticdentistryguide.co.uk
David Zid, an ACE, APG certified trainer, has collaborated with orthopedic surgeon, Thomas H. Mallory, M.D., who is afflicted with Parkinson’s disease, in the development of a Parkinson’s specific fitness program designed to proactively minimize tremors and improve flexibility, stability, balance and strength. Zid demonstrates each move and provides recommendations for exercise frequency, modification and how to adjust the workout as one improves. Parkinson’s patients participating in Zid’s firn
Rating: (out of 3 reviews)
List Price: $ 24.95
Price: $ 24.95
Parkinson’s research advances at Buck Institute
Scientists at the Buck Institute for Age Research in Novato reported a new advance Monday in their search for treatment of Parkinson’s disease. Read more on Marin Independent Journal
Question by Courtney: What is the genetic basis for Parkinson’s Disease?
I am currently working on a project for my biology class on parkinson’s disease. in one of the boxes i have to put the genetic basis for PD.
(for example, is it sex linked, controlled by one or multiple alleles, non disjunction, random mutation of a certain gene, etc.)
I can’t seem to find these answers anywhere.
Any answers or suggestions of sites would be great, thanks.
Best answer:
Answer by Mags The jury is still out for the full genetic basis for PD.
The latest concept is that Parkinson’s disease is genetic and can remain dormant for generations. One reason that PD was not thought to be primarily or strictly genetic in nature was that sometimes many generations were skipped. It is possible that other factors have to act as the trigger. Environmental, medications, heavy metal exposure and the like.
I put the best link last but read down first as the expository info will be in the earlier links.
The first link is for two studies completed in 2008 by two researchers from the Mayo clinic where PD studies have been conducted for many years.
In one study a mutation of LRRK2-R1628P has been traced back to 2,500 BC. LRRK2-G2385R has been traced back 4,500 years.
Another study found that LRRK2-R1441C can increase the chances of developing PD by 10X.
http://www.scientistlive.com/European-Sc…
Next let’s go to the LRRK2 (leucine-rich repeat kinease2) autosomal dominant mutation which you can read about here for starters because it has been identified in almost 5% of PD cases:
http://www.thelancet.com/journals/lancet…
There is a study currently recruiting for a LRRK2 study in Maryland:
http://clinicaltrials.gov/ct2/show/NCT00…
Glucocerebrosidase gene
GBA mutations (N370S, L444P, 84GG, IVS+1, V394L, and R496H) that are most common among Ashkenazi Jews
http://www.thelancet.com/journals/laneur…
70117-0/abstract
and GBA-Gly2019SER here:
http://content.nejm.org/cgi/content/shor…
A study published in 2007 indicated that genetic mutations were 2X as common in YOPD (Young or early onset Parkinson’s Disease) and in people of Jewish Ancestry – specifically Ashkenazic)
Here is an abstract link about DJ-1, an autosomal recessive linked to PD. The abstract also references PARK6 and PARK7:
http://jnnp.bmj.com/cgi/content/abstract…
The best gene data base is here – it is a public and you can link to the site to see it:
http://datam.i2r.a-star.edu.sg/mdpd/stat…
In this chart you will see the gene, the number of reports and ethnic groups
Naturally it begins with LRRK2. PARK2 followed by SNCA, CYP2D6, PINK1, MAPT, UCHL1, MAOB, PARK7 and APOE
It then lists the top 10 genes with the most variants followed by the top 10 with the most negative reports.
There are several other comparisons you can do at the site, it is amazing. Check it out.
While it is true that more men than women develop PD that may be because of a bioprotectiveness of estrogen. Which of course ends at sometime with menopause.
You should probably search for Chinese – HAN – gene – Parkinson’s disease. You might find the rest of the answer which you need. There are also several familial studies. I have read the abstracts but not the full studies.
Here are a few which should help:
http://www.ncbi.nlm.nih.gov/pubmed/12730996
Here’s a familial study from Italy but it is older, 2003:
To properly search just enter each term with Parkinson’s disease and you will find a host of abstracts and some articles about the abstracts. You will not find definitive answers because they aren’t there yet. Pd is a complicated disease.
What do you think? Answer below!
Stretching for the Parkinson’s 5K Walk and Fun Run 2008
PROJECT: ON/OFF Living & Coping with Young O nset Parkinson’s Disease Directed, produced, filmed, and edited by Tim Costello. THIS IS A SHORT, NON FINAL PRODCUT, USED AS A TEASER USED TO FIND THE FUNDING NEEDED, 000, TO FINISH THE PROJECT (ONE HOUR DOCUMENTARY). FINAL PROJECT WILL DOCUMENT 6 YOUNG ONSET “LIVING” VICE “SUFFERING” FROM PARKINSON’S DISEASE. FILMMAKER: Tim Costello PROJECT IDEA DEVOLOPED BY: TOM BERDINE SPONSOR/FUND SOURCE: TBD FACTS It is estim ated that 1.5 m illion Am ericans are currently diagnosed w ith Parkinson’s disease. 50000 to 60000 more are diagnosed each year. It is believed that 10% of these are under 49, w ith a good m ajority in their late teens, 20′s, 30′s, and 40′s. These individuals are graduating college, starting careers, relationships, families, and trying to build a future for themselves and their loved ones. These are referred to as being diagnosed as “young onset”. ABOUT THE PROJECT The film project is a documentary that will give the audience a front row seat into the normally private lives of six people diagnosed w ith young onset Parkinson’s disease. The film w ill be unscripted, real, at times humorous and other times shocking. It will show them living life as close to or better then before diagnosis. It will show them accommodating these symptoms and side effects despite the daily challenges thrown at them by the symptoms of the disease and side effects of the various medications. Video Rating: 4 / 5
The Repercussions of Parkinson’s Disease in Oral Health
An estimated 50,000 Americans are diagnosed with Parkinson’s Disease each year. It generally affects people in their middle to late years. It is a kind of disorder that causes uncontrollable muscle movements, tremors, muscle rigidity and may even lead to severe memory loss. The patient’s speech and motors skills can also suffer.
Parkinson’s Disease is a degenerative disorder that affects the body’s nervous system which in turn is responsible for the relay of communication between the brain and the muscles. A disruption occurs in the nervous system that gravely affects reactions and movements of the muscles leading to such abnormalities as tremors and rigidity.
The disease usually starts to show symptoms with just a few individual muscle tremors. Sometimes it can manifest itself due to lack of muscle controls that are gradually visible to other people. This can be lack of facial expressions, mumbling sounds while talking, and even the non-movement of the arms while walking. These are simple symptoms that may usually mean the starting occurrence of Parkinson’s Disease.
A patient suffering from this disease may likewise suffer from very poor dental hygiene. While it is true that most people who have Parkinson’s Disease are already old and therefore no longer requires a set of perfect teeth, the fact remains that oral health is an important factor on the overall health condition of an individual. Therefore it is of high importance that people suffering from this disease still get the right amount of dental hygiene.
Because of the weakness of the muscles, a patient may not be able to brush his own teeth. As such, he may require the assistance of another person preferably from a well-trained professional like a caregiver. An expert assistance is necessary to make sure that the patient gets the best dental hygiene even for his condition. This may mean brushing the patient’s teeth, flossing them and administering any required medicines.
Another important point to consider is that some Parkinson’s Disease patients are prescribed to take drugs that can cause xerostomia. Xerostomia is more commonly called dry mouth. The saliva is an important component of a good oral hygiene as it helps clean the mouth by fighting off bacteria. Now, a person who suffers from xerostomia has higher risk of developing tooth decay, halitosis and other periodontal diseases and disorders. If you have constant dry mouth, your dentist can prescribe you with a medicine that can stimulate the production of more saliva as well as prescribing you with fluoride treatments to help battle tooth decay.
Also, due to the fact that Parkinson’s Disease patients may suffer from tremors, muscle rigidity and weakness, as well as feel agitated, it will be harder to keep him still in the dentist’s chair. This is very important because it makes it harder for the dentist to conduct the necessary dental procedures. Some form of equipment and contraptions may be used to keep the patient still. For much worse situations, the dentist may require to sedate his patient to avoid any unnecessary movements during the treatment.
If you want to learn more about Parkinsons disease and its implications when it comes to oral health get straight answers from professionals who also provide info on the correlation between Osseous Surgery and dental health, visit us at http://www.cosmeticdentistryguide.co.uk
Genetic link discovered between immune system, Parkinson’s disease
Scientists have discovered new evidence that Parkinson’s disease may have an infectious or autoimmune origin. Read more on Science Daily
Question by The Unpublished Poet: Why do people think that those with movement disorders like Parkinson’s Disease are faking it to get attention?
I think I have something similar to familial PKD (which is similar to Parkinson’s Disease, except sporadic).
However, there are people who think that people with movement disorders are faking it to get attention.
Why do they think that?
Best answer:
Answer by Croatian ♠ Angel ignorance…just try and don’t let them get to you
Know better? Leave your own answer in the comments!
Stretching for the Parkinson’s 5K Walk and Fun Run 2008
PROJECT: ON/OFF Living & Coping with Young O nset Parkinson’s Disease Directed, produced, filmed, and edited by Tim Costello. THIS IS A SHORT, NON FINAL PRODCUT, USED AS A TEASER USED TO FIND THE FUNDING NEEDED, 000, TO FINISH THE PROJECT (ONE HOUR DOCUMENTARY). FINAL PROJECT WILL DOCUMENT 6 YOUNG ONSET “LIVING” VICE “SUFFERING” FROM PARKINSON’S DISEASE. FILMMAKER: Tim Costello PROJECT IDEA DEVOLOPED BY: TOM BERDINE SPONSOR/FUND SOURCE: TBD FACTS It is estim ated that 1.5 m illion Am ericans are currently diagnosed w ith Parkinson’s disease. 50000 to 60000 more are diagnosed each year. It is believed that 10% of these are under 49, w ith a good m ajority in their late teens, 20′s, 30′s, and 40′s. These individuals are graduating college, starting careers, relationships, families, and trying to build a future for themselves and their loved ones. These are referred to as being diagnosed as “young onset”. ABOUT THE PROJECT The film project is a documentary that will give the audience a front row seat into the normally private lives of six people diagnosed w ith young onset Parkinson’s disease. The film w ill be unscripted, real, at times humorous and other times shocking. It will show them living life as close to or better then before diagnosis. It will show them accommodating these symptoms and side effects despite the daily challenges thrown at them by the symptoms of the disease and side effects of the various medications. Video Rating: 4 / 5
The Repercussions of Parkinson’s Disease in Oral Health
An estimated 50,000 Americans are diagnosed with Parkinson’s Disease each year. It generally affects people in their middle to late years. It is a kind of disorder that causes uncontrollable muscle movements, tremors, muscle rigidity and may even lead to severe memory loss. The patient’s speech and motors skills can also suffer.
Parkinson’s Disease is a degenerative disorder that affects the body’s nervous system which in turn is responsible for the relay of communication between the brain and the muscles. A disruption occurs in the nervous system that gravely affects reactions and movements of the muscles leading to such abnormalities as tremors and rigidity.
The disease usually starts to show symptoms with just a few individual muscle tremors. Sometimes it can manifest itself due to lack of muscle controls that are gradually visible to other people. This can be lack of facial expressions, mumbling sounds while talking, and even the non-movement of the arms while walking. These are simple symptoms that may usually mean the starting occurrence of Parkinson’s Disease.
A patient suffering from this disease may likewise suffer from very poor dental hygiene. While it is true that most people who have Parkinson’s Disease are already old and therefore no longer requires a set of perfect teeth, the fact remains that oral health is an important factor on the overall health condition of an individual. Therefore it is of high importance that people suffering from this disease still get the right amount of dental hygiene.
Because of the weakness of the muscles, a patient may not be able to brush his own teeth. As such, he may require the assistance of another person preferably from a well-trained professional like a caregiver. An expert assistance is necessary to make sure that the patient gets the best dental hygiene even for his condition. This may mean brushing the patient’s teeth, flossing them and administering any required medicines.
Another important point to consider is that some Parkinson’s Disease patients are prescribed to take drugs that can cause xerostomia. Xerostomia is more commonly called dry mouth. The saliva is an important component of a good oral hygiene as it helps clean the mouth by fighting off bacteria. Now, a person who suffers from xerostomia has higher risk of developing tooth decay, halitosis and other periodontal diseases and disorders. If you have constant dry mouth, your dentist can prescribe you with a medicine that can stimulate the production of more saliva as well as prescribing you with fluoride treatments to help battle tooth decay.
Also, due to the fact that Parkinson’s Disease patients may suffer from tremors, muscle rigidity and weakness, as well as feel agitated, it will be harder to keep him still in the dentist’s chair. This is very important because it makes it harder for the dentist to conduct the necessary dental procedures. Some form of equipment and contraptions may be used to keep the patient still. For much worse situations, the dentist may require to sedate his patient to avoid any unnecessary movements during the treatment.
If you want to learn more about Parkinsons disease and its implications when it comes to oral health get straight answers from professionals who also provide info on the correlation between Osseous Surgery and dental health, visit us at http://www.cosmeticdentistryguide.co.uk
Immune System Genes Linked To Parkinson’s Disease
An international team of researchers conducting a genome-wide association study (GWAS) has discovered that common variants in immune system genes are linked to Parkinson’s disease. The study was the work of the NeuroGenetics Research Consortium, led by Dr Haydeh Payami, a research scientist at the Health Wadsworth Center and professor in the School of Public Health, both in the New York State … Read more on Medical News Today
Question by The Unpublished Poet: Why do people think that those with movement disorders like Parkinson’s Disease are faking it to get attention?
I think I have something similar to familial PKD (which is similar to Parkinson’s Disease, except sporadic).
However, there are people who think that people with movement disorders are faking it to get attention.
Why do they think that?
Best answer:
Answer by Croatian ♠ Angel ignorance…just try and don’t let them get to you
Add your own answer in the comments!
Stretching for the Parkinson’s 5K Walk and Fun Run 2008
PROJECT: ON/OFF Living & Coping with Young O nset Parkinson’s Disease Directed, produced, filmed, and edited by Tim Costello. THIS IS A SHORT, NON FINAL PRODCUT, USED AS A TEASER USED TO FIND THE FUNDING NEEDED, 000, TO FINISH THE PROJECT (ONE HOUR DOCUMENTARY). FINAL PROJECT WILL DOCUMENT 6 YOUNG ONSET “LIVING” VICE “SUFFERING” FROM PARKINSON’S DISEASE. FILMMAKER: Tim Costello PROJECT IDEA DEVOLOPED BY: TOM BERDINE SPONSOR/FUND SOURCE: TBD FACTS It is estim ated that 1.5 m illion Am ericans are currently diagnosed w ith Parkinson’s disease. 50000 to 60000 more are diagnosed each year. It is believed that 10% of these are under 49, w ith a good m ajority in their late teens, 20′s, 30′s, and 40′s. These individuals are graduating college, starting careers, relationships, families, and trying to build a future for themselves and their loved ones. These are referred to as being diagnosed as “young onset”. ABOUT THE PROJECT The film project is a documentary that will give the audience a front row seat into the normally private lives of six people diagnosed w ith young onset Parkinson’s disease. The film w ill be unscripted, real, at times humorous and other times shocking. It will show them living life as close to or better then before diagnosis. It will show them accommodating these symptoms and side effects despite the daily challenges thrown at them by the symptoms of the disease and side effects of the various medications.
The Repercussions of Parkinson’s Disease in Oral Health
An estimated 50,000 Americans are diagnosed with Parkinson’s Disease each year. It generally affects people in their middle to late years. It is a kind of disorder that causes uncontrollable muscle movements, tremors, muscle rigidity and may even lead to severe memory loss. The patient’s speech and motors skills can also suffer.
Parkinson’s Disease is a degenerative disorder that affects the body’s nervous system which in turn is responsible for the relay of communication between the brain and the muscles. A disruption occurs in the nervous system that gravely affects reactions and movements of the muscles leading to such abnormalities as tremors and rigidity.
The disease usually starts to show symptoms with just a few individual muscle tremors. Sometimes it can manifest itself due to lack of muscle controls that are gradually visible to other people. This can be lack of facial expressions, mumbling sounds while talking, and even the non-movement of the arms while walking. These are simple symptoms that may usually mean the starting occurrence of Parkinson’s Disease.
A patient suffering from this disease may likewise suffer from very poor dental hygiene. While it is true that most people who have Parkinson’s Disease are already old and therefore no longer requires a set of perfect teeth, the fact remains that oral health is an important factor on the overall health condition of an individual. Therefore it is of high importance that people suffering from this disease still get the right amount of dental hygiene.
Because of the weakness of the muscles, a patient may not be able to brush his own teeth. As such, he may require the assistance of another person preferably from a well-trained professional like a caregiver. An expert assistance is necessary to make sure that the patient gets the best dental hygiene even for his condition. This may mean brushing the patient’s teeth, flossing them and administering any required medicines.
Another important point to consider is that some Parkinson’s Disease patients are prescribed to take drugs that can cause xerostomia. Xerostomia is more commonly called dry mouth. The saliva is an important component of a good oral hygiene as it helps clean the mouth by fighting off bacteria. Now, a person who suffers from xerostomia has higher risk of developing tooth decay, halitosis and other periodontal diseases and disorders. If you have constant dry mouth, your dentist can prescribe you with a medicine that can stimulate the production of more saliva as well as prescribing you with fluoride treatments to help battle tooth decay.
Also, due to the fact that Parkinson’s Disease patients may suffer from tremors, muscle rigidity and weakness, as well as feel agitated, it will be harder to keep him still in the dentist’s chair. This is very important because it makes it harder for the dentist to conduct the necessary dental procedures. Some form of equipment and contraptions may be used to keep the patient still. For much worse situations, the dentist may require to sedate his patient to avoid any unnecessary movements during the treatment.
If you want to learn more about Parkinsons disease and its implications when it comes to oral health get straight answers from professionals who also provide info on the correlation between Osseous Surgery and dental health, visit us at http://www.cosmeticdentistryguide.co.uk
Tango helps fight Parkinson’s Disease
Wilfried Adelt came home one day from an exercise class in 2007 and announced he was joining a tango class. Read more on Suburban Journals
Question by The Unpublished Poet: Why do people think that those with movement disorders like Parkinson’s Disease are faking it to get attention?
I think I have something similar to familial PKD (which is similar to Parkinson’s Disease, except sporadic).
However, there are people who think that people with movement disorders are faking it to get attention.
Why do they think that?
Best answer:
Answer by Croatian ♠ Angel ignorance…just try and don’t let them get to you
Know better? Leave your own answer in the comments!
Stretching for the Parkinson’s 5K Walk and Fun Run 2008
PROJECT: ON/OFF Living & Coping with Young O nset Parkinson’s Disease Directed, produced, filmed, and edited by Tim Costello. THIS IS A SHORT, NON FINAL PRODCUT, USED AS A TEASER USED TO FIND THE FUNDING NEEDED, 000, TO FINISH THE PROJECT (ONE HOUR DOCUMENTARY). FINAL PROJECT WILL DOCUMENT 6 YOUNG ONSET “LIVING” VICE “SUFFERING” FROM PARKINSON’S DISEASE. FILMMAKER: Tim Costello PROJECT IDEA DEVOLOPED BY: TOM BERDINE SPONSOR/FUND SOURCE: TBD FACTS It is estim ated that 1.5 m illion Am ericans are currently diagnosed w ith Parkinson’s disease. 50000 to 60000 more are diagnosed each year. It is believed that 10% of these are under 49, w ith a good m ajority in their late teens, 20′s, 30′s, and 40′s. These individuals are graduating college, starting careers, relationships, families, and trying to build a future for themselves and their loved ones. These are referred to as being diagnosed as “young onset”. ABOUT THE PROJECT The film project is a documentary that will give the audience a front row seat into the normally private lives of six people diagnosed w ith young onset Parkinson’s disease. The film w ill be unscripted, real, at times humorous and other times shocking. It will show them living life as close to or better then before diagnosis. It will show them accommodating these symptoms and side effects despite the daily challenges thrown at them by the symptoms of the disease and side effects of the various medications. Video Rating: 4 / 5
The Repercussions of Parkinson’s Disease in Oral Health
An estimated 50,000 Americans are diagnosed with Parkinson’s Disease each year. It generally affects people in their middle to late years. It is a kind of disorder that causes uncontrollable muscle movements, tremors, muscle rigidity and may even lead to severe memory loss. The patient’s speech and motors skills can also suffer.
Parkinson’s Disease is a degenerative disorder that affects the body’s nervous system which in turn is responsible for the relay of communication between the brain and the muscles. A disruption occurs in the nervous system that gravely affects reactions and movements of the muscles leading to such abnormalities as tremors and rigidity.
The disease usually starts to show symptoms with just a few individual muscle tremors. Sometimes it can manifest itself due to lack of muscle controls that are gradually visible to other people. This can be lack of facial expressions, mumbling sounds while talking, and even the non-movement of the arms while walking. These are simple symptoms that may usually mean the starting occurrence of Parkinson’s Disease.
A patient suffering from this disease may likewise suffer from very poor dental hygiene. While it is true that most people who have Parkinson’s Disease are already old and therefore no longer requires a set of perfect teeth, the fact remains that oral health is an important factor on the overall health condition of an individual. Therefore it is of high importance that people suffering from this disease still get the right amount of dental hygiene.
Because of the weakness of the muscles, a patient may not be able to brush his own teeth. As such, he may require the assistance of another person preferably from a well-trained professional like a caregiver. An expert assistance is necessary to make sure that the patient gets the best dental hygiene even for his condition. This may mean brushing the patient’s teeth, flossing them and administering any required medicines.
Another important point to consider is that some Parkinson’s Disease patients are prescribed to take drugs that can cause xerostomia. Xerostomia is more commonly called dry mouth. The saliva is an important component of a good oral hygiene as it helps clean the mouth by fighting off bacteria. Now, a person who suffers from xerostomia has higher risk of developing tooth decay, halitosis and other periodontal diseases and disorders. If you have constant dry mouth, your dentist can prescribe you with a medicine that can stimulate the production of more saliva as well as prescribing you with fluoride treatments to help battle tooth decay.
Also, due to the fact that Parkinson’s Disease patients may suffer from tremors, muscle rigidity and weakness, as well as feel agitated, it will be harder to keep him still in the dentist’s chair. This is very important because it makes it harder for the dentist to conduct the necessary dental procedures. Some form of equipment and contraptions may be used to keep the patient still. For much worse situations, the dentist may require to sedate his patient to avoid any unnecessary movements during the treatment.
If you want to learn more about Parkinsons disease and its implications when it comes to oral health get straight answers from professionals who also provide info on the correlation between Osseous Surgery and dental health, visit us at http://www.cosmeticdentistryguide.co.uk
Love and Other Drugs, Now With Parkinson’s Disease
The first trailer for Love and Other Drugs was just released last week, and it’s all Jake Gyllenhaal and Anne Hathaway banging, falling in love, and being generally charming. But maybe that was all a bit too light. Today, a second trailer for the film has been released, this one making explicit that Hathaway’s character has Parkinson’s disease (and that Gyllenhaal sells lots and lots of Viagra … Read more on Vulture
Question by The Unpublished Poet: Why do people think that those with movement disorders like Parkinson’s Disease are faking it to get attention?
I think I have something similar to familial PKD (which is similar to Parkinson’s Disease, except sporadic).
However, there are people who think that people with movement disorders are faking it to get attention.
Why do they think that?
Best answer:
Answer by Croatian ♠ Angel ignorance…just try and don’t let them get to you
Give your answer to this question below!
Stretching for the Parkinson’s 5K Walk and Fun Run 2008
PROJECT: ON/OFF Living & Coping with Young O nset Parkinson’s Disease Directed, produced, filmed, and edited by Tim Costello. THIS IS A SHORT, NON FINAL PRODCUT, USED AS A TEASER USED TO FIND THE FUNDING NEEDED, 000, TO FINISH THE PROJECT (ONE HOUR DOCUMENTARY). FINAL PROJECT WILL DOCUMENT 6 YOUNG ONSET “LIVING” VICE “SUFFERING” FROM PARKINSON’S DISEASE. FILMMAKER: Tim Costello PROJECT IDEA DEVOLOPED BY: TOM BERDINE SPONSOR/FUND SOURCE: TBD FACTS It is estim ated that 1.5 m illion Am ericans are currently diagnosed w ith Parkinson’s disease. 50000 to 60000 more are diagnosed each year. It is believed that 10% of these are under 49, w ith a good m ajority in their late teens, 20′s, 30′s, and 40′s. These individuals are graduating college, starting careers, relationships, families, and trying to build a future for themselves and their loved ones. These are referred to as being diagnosed as “young onset”. ABOUT THE PROJECT The film project is a documentary that will give the audience a front row seat into the normally private lives of six people diagnosed w ith young onset Parkinson’s disease. The film w ill be unscripted, real, at times humorous and other times shocking. It will show them living life as close to or better then before diagnosis. It will show them accommodating these symptoms and side effects despite the daily challenges thrown at them by the symptoms of the disease and side effects of the various medications. Video Rating: 4 / 5
The Repercussions of Parkinson’s Disease in Oral Health
An estimated 50,000 Americans are diagnosed with Parkinson’s Disease each year. It generally affects people in their middle to late years. It is a kind of disorder that causes uncontrollable muscle movements, tremors, muscle rigidity and may even lead to severe memory loss. The patient’s speech and motors skills can also suffer.
Parkinson’s Disease is a degenerative disorder that affects the body’s nervous system which in turn is responsible for the relay of communication between the brain and the muscles. A disruption occurs in the nervous system that gravely affects reactions and movements of the muscles leading to such abnormalities as tremors and rigidity.
The disease usually starts to show symptoms with just a few individual muscle tremors. Sometimes it can manifest itself due to lack of muscle controls that are gradually visible to other people. This can be lack of facial expressions, mumbling sounds while talking, and even the non-movement of the arms while walking. These are simple symptoms that may usually mean the starting occurrence of Parkinson’s Disease.
A patient suffering from this disease may likewise suffer from very poor dental hygiene. While it is true that most people who have Parkinson’s Disease are already old and therefore no longer requires a set of perfect teeth, the fact remains that oral health is an important factor on the overall health condition of an individual. Therefore it is of high importance that people suffering from this disease still get the right amount of dental hygiene.
Because of the weakness of the muscles, a patient may not be able to brush his own teeth. As such, he may require the assistance of another person preferably from a well-trained professional like a caregiver. An expert assistance is necessary to make sure that the patient gets the best dental hygiene even for his condition. This may mean brushing the patient’s teeth, flossing them and administering any required medicines.
Another important point to consider is that some Parkinson’s Disease patients are prescribed to take drugs that can cause xerostomia. Xerostomia is more commonly called dry mouth. The saliva is an important component of a good oral hygiene as it helps clean the mouth by fighting off bacteria. Now, a person who suffers from xerostomia has higher risk of developing tooth decay, halitosis and other periodontal diseases and disorders. If you have constant dry mouth, your dentist can prescribe you with a medicine that can stimulate the production of more saliva as well as prescribing you with fluoride treatments to help battle tooth decay.
Also, due to the fact that Parkinson’s Disease patients may suffer from tremors, muscle rigidity and weakness, as well as feel agitated, it will be harder to keep him still in the dentist’s chair. This is very important because it makes it harder for the dentist to conduct the necessary dental procedures. Some form of equipment and contraptions may be used to keep the patient still. For much worse situations, the dentist may require to sedate his patient to avoid any unnecessary movements during the treatment.
If you want to learn more about Parkinsons disease and its implications when it comes to oral health get straight answers from professionals who also provide info on the correlation between Osseous Surgery and dental health, visit us at http://www.cosmeticdentistryguide.co.uk
David Zid, an ACE, APG certified trainer, has collaborated with orthopedic surgeon, Thomas H. Mallory, M.D., who is afflicted with Parkinson’s disease, in the development of a Parkinson’s specific fitness program designed to proactively minimize tremors and improve flexibility, stability, balance and strength. Zid demonstrates each move and provides recommendations for exercise frequency, modification and how to adjust the workout as one improves. Parkinson’s patients participating in Zid’s firn
Rating: (out of 3 reviews)
List Price: $ 24.95
Price: $ 24.95
Love and Other Drugs, Now With Parkinson’s Disease
The first trailer for Love and Other Drugs was just released last week, and it’s all Jake Gyllenhaal and Anne Hathaway banging, falling in love, and being generally charming. But maybe that was all a bit too light. Today, a second trailer for the film has been released, this one making explicit that Hathaway’s character has Parkinson’s disease (and that Gyllenhaal sells lots and lots of Viagra … Read more on Vulture
Question by The Unpublished Poet: Why do people think that those with movement disorders like Parkinson’s Disease are faking it to get attention?
I think I have something similar to familial PKD (which is similar to Parkinson’s Disease, except sporadic).
However, there are people who think that people with movement disorders are faking it to get attention.
Why do they think that?
Best answer:
Answer by Croatian ♠ Angel ignorance…just try and don’t let them get to you
What do you think? Answer below!
Stretching for the Parkinson’s 5K Walk and Fun Run 2008
PROJECT: ON/OFF Living & Coping with Young O nset Parkinson’s Disease Directed, produced, filmed, and edited by Tim Costello. THIS IS A SHORT, NON FINAL PRODCUT, USED AS A TEASER USED TO FIND THE FUNDING NEEDED, 000, TO FINISH THE PROJECT (ONE HOUR DOCUMENTARY). FINAL PROJECT WILL DOCUMENT 6 YOUNG ONSET “LIVING” VICE “SUFFERING” FROM PARKINSON’S DISEASE. FILMMAKER: Tim Costello PROJECT IDEA DEVOLOPED BY: TOM BERDINE SPONSOR/FUND SOURCE: TBD FACTS It is estim ated that 1.5 m illion Am ericans are currently diagnosed w ith Parkinson’s disease. 50000 to 60000 more are diagnosed each year. It is believed that 10% of these are under 49, w ith a good m ajority in their late teens, 20′s, 30′s, and 40′s. These individuals are graduating college, starting careers, relationships, families, and trying to build a future for themselves and their loved ones. These are referred to as being diagnosed as “young onset”. ABOUT THE PROJECT The film project is a documentary that will give the audience a front row seat into the normally private lives of six people diagnosed w ith young onset Parkinson’s disease. The film w ill be unscripted, real, at times humorous and other times shocking. It will show them living life as close to or better then before diagnosis. It will show them accommodating these symptoms and side effects despite the daily challenges thrown at them by the symptoms of the disease and side effects of the various medications. Video Rating: 4 / 5
The Repercussions of Parkinson’s Disease in Oral Health
An estimated 50,000 Americans are diagnosed with Parkinson’s Disease each year. It generally affects people in their middle to late years. It is a kind of disorder that causes uncontrollable muscle movements, tremors, muscle rigidity and may even lead to severe memory loss. The patient’s speech and motors skills can also suffer.
Parkinson’s Disease is a degenerative disorder that affects the body’s nervous system which in turn is responsible for the relay of communication between the brain and the muscles. A disruption occurs in the nervous system that gravely affects reactions and movements of the muscles leading to such abnormalities as tremors and rigidity.
The disease usually starts to show symptoms with just a few individual muscle tremors. Sometimes it can manifest itself due to lack of muscle controls that are gradually visible to other people. This can be lack of facial expressions, mumbling sounds while talking, and even the non-movement of the arms while walking. These are simple symptoms that may usually mean the starting occurrence of Parkinson’s Disease.
A patient suffering from this disease may likewise suffer from very poor dental hygiene. While it is true that most people who have Parkinson’s Disease are already old and therefore no longer requires a set of perfect teeth, the fact remains that oral health is an important factor on the overall health condition of an individual. Therefore it is of high importance that people suffering from this disease still get the right amount of dental hygiene.
Because of the weakness of the muscles, a patient may not be able to brush his own teeth. As such, he may require the assistance of another person preferably from a well-trained professional like a caregiver. An expert assistance is necessary to make sure that the patient gets the best dental hygiene even for his condition. This may mean brushing the patient’s teeth, flossing them and administering any required medicines.
Another important point to consider is that some Parkinson’s Disease patients are prescribed to take drugs that can cause xerostomia. Xerostomia is more commonly called dry mouth. The saliva is an important component of a good oral hygiene as it helps clean the mouth by fighting off bacteria. Now, a person who suffers from xerostomia has higher risk of developing tooth decay, halitosis and other periodontal diseases and disorders. If you have constant dry mouth, your dentist can prescribe you with a medicine that can stimulate the production of more saliva as well as prescribing you with fluoride treatments to help battle tooth decay.
Also, due to the fact that Parkinson’s Disease patients may suffer from tremors, muscle rigidity and weakness, as well as feel agitated, it will be harder to keep him still in the dentist’s chair. This is very important because it makes it harder for the dentist to conduct the necessary dental procedures. Some form of equipment and contraptions may be used to keep the patient still. For much worse situations, the dentist may require to sedate his patient to avoid any unnecessary movements during the treatment.
If you want to learn more about Parkinsons disease and its implications when it comes to oral health get straight answers from professionals who also provide info on the correlation between Osseous Surgery and dental health, visit us at http://www.cosmeticdentistryguide.co.uk
David Zid, an ACE, APG certified trainer, has collaborated with orthopedic surgeon, Thomas H. Mallory, M.D., who is afflicted with Parkinson’s disease, in the development of a Parkinson’s specific fitness program designed to proactively minimize tremors and improve flexibility, stability, balance and strength. Zid demonstrates each move and provides recommendations for exercise frequency, modification and how to adjust the workout as one improves. Parkinson’s patients participating in Zid’s firn
Rating: (out of 3 reviews)
List Price: $ 24.95
Price: $ 24.95
Fighting Parkinson’s
Barbara Larsen’s job is to help people rediscover that natural rhythm. The Nevada City resident and author teaches exercise classes to people suffering from Parkinson’s and their caretakers. Read more on The Grass Valley Union
Question by Courtney: What is the genetic basis for Parkinson’s Disease?
I am currently working on a project for my biology class on parkinson’s disease. in one of the boxes i have to put the genetic basis for PD.
(for example, is it sex linked, controlled by one or multiple alleles, non disjunction, random mutation of a certain gene, etc.)
I can’t seem to find these answers anywhere.
Any answers or suggestions of sites would be great, thanks.
Best answer:
Answer by Mags The jury is still out for the full genetic basis for PD.
The latest concept is that Parkinson’s disease is genetic and can remain dormant for generations. One reason that PD was not thought to be primarily or strictly genetic in nature was that sometimes many generations were skipped. It is possible that other factors have to act as the trigger. Environmental, medications, heavy metal exposure and the like.
I put the best link last but read down first as the expository info will be in the earlier links.
The first link is for two studies completed in 2008 by two researchers from the Mayo clinic where PD studies have been conducted for many years.
In one study a mutation of LRRK2-R1628P has been traced back to 2,500 BC. LRRK2-G2385R has been traced back 4,500 years.
Another study found that LRRK2-R1441C can increase the chances of developing PD by 10X.
http://www.scientistlive.com/European-Sc…
Next let’s go to the LRRK2 (leucine-rich repeat kinease2) autosomal dominant mutation which you can read about here for starters because it has been identified in almost 5% of PD cases:
http://www.thelancet.com/journals/lancet…
There is a study currently recruiting for a LRRK2 study in Maryland:
http://clinicaltrials.gov/ct2/show/NCT00…
Glucocerebrosidase gene
GBA mutations (N370S, L444P, 84GG, IVS+1, V394L, and R496H) that are most common among Ashkenazi Jews
http://www.thelancet.com/journals/laneur…
70117-0/abstract
and GBA-Gly2019SER here:
http://content.nejm.org/cgi/content/shor…
A study published in 2007 indicated that genetic mutations were 2X as common in YOPD (Young or early onset Parkinson’s Disease) and in people of Jewish Ancestry – specifically Ashkenazic)
Here is an abstract link about DJ-1, an autosomal recessive linked to PD. The abstract also references PARK6 and PARK7:
http://jnnp.bmj.com/cgi/content/abstract…
The best gene data base is here – it is a public and you can link to the site to see it:
http://datam.i2r.a-star.edu.sg/mdpd/stat…
In this chart you will see the gene, the number of reports and ethnic groups
Naturally it begins with LRRK2. PARK2 followed by SNCA, CYP2D6, PINK1, MAPT, UCHL1, MAOB, PARK7 and APOE
It then lists the top 10 genes with the most variants followed by the top 10 with the most negative reports.
There are several other comparisons you can do at the site, it is amazing. Check it out.
While it is true that more men than women develop PD that may be because of a bioprotectiveness of estrogen. Which of course ends at sometime with menopause.
You should probably search for Chinese – HAN – gene – Parkinson’s disease. You might find the rest of the answer which you need. There are also several familial studies. I have read the abstracts but not the full studies.
Here are a few which should help:
http://www.ncbi.nlm.nih.gov/pubmed/12730996
Here’s a familial study from Italy but it is older, 2003:
To properly search just enter each term with Parkinson’s disease and you will find a host of abstracts and some articles about the abstracts. You will not find definitive answers because they aren’t there yet. Pd is a complicated disease.
Give your answer to this question below!
Stretching for the Parkinson’s 5K Walk and Fun Run 2008
PROJECT: ON/OFF Living & Coping with Young O nset Parkinson’s Disease Directed, produced, filmed, and edited by Tim Costello. THIS IS A SHORT, NON FINAL PRODCUT, USED AS A TEASER USED TO FIND THE FUNDING NEEDED, 000, TO FINISH THE PROJECT (ONE HOUR DOCUMENTARY). FINAL PROJECT WILL DOCUMENT 6 YOUNG ONSET “LIVING” VICE “SUFFERING” FROM PARKINSON’S DISEASE. FILMMAKER: Tim Costello PROJECT IDEA DEVOLOPED BY: TOM BERDINE SPONSOR/FUND SOURCE: TBD FACTS It is estim ated that 1.5 m illion Am ericans are currently diagnosed w ith Parkinson’s disease. 50000 to 60000 more are diagnosed each year. It is believed that 10% of these are under 49, w ith a good m ajority in their late teens, 20′s, 30′s, and 40′s. These individuals are graduating college, starting careers, relationships, families, and trying to build a future for themselves and their loved ones. These are referred to as being diagnosed as “young onset”. ABOUT THE PROJECT The film project is a documentary that will give the audience a front row seat into the normally private lives of six people diagnosed w ith young onset Parkinson’s disease. The film w ill be unscripted, real, at times humorous and other times shocking. It will show them living life as close to or better then before diagnosis. It will show them accommodating these symptoms and side effects despite the daily challenges thrown at them by the symptoms of the disease and side effects of the various medications. Video Rating: 4 / 5
The Repercussions of Parkinson’s Disease in Oral Health
An estimated 50,000 Americans are diagnosed with Parkinson’s Disease each year. It generally affects people in their middle to late years. It is a kind of disorder that causes uncontrollable muscle movements, tremors, muscle rigidity and may even lead to severe memory loss. The patient’s speech and motors skills can also suffer.
Parkinson’s Disease is a degenerative disorder that affects the body’s nervous system which in turn is responsible for the relay of communication between the brain and the muscles. A disruption occurs in the nervous system that gravely affects reactions and movements of the muscles leading to such abnormalities as tremors and rigidity.
The disease usually starts to show symptoms with just a few individual muscle tremors. Sometimes it can manifest itself due to lack of muscle controls that are gradually visible to other people. This can be lack of facial expressions, mumbling sounds while talking, and even the non-movement of the arms while walking. These are simple symptoms that may usually mean the starting occurrence of Parkinson’s Disease.
A patient suffering from this disease may likewise suffer from very poor dental hygiene. While it is true that most people who have Parkinson’s Disease are already old and therefore no longer requires a set of perfect teeth, the fact remains that oral health is an important factor on the overall health condition of an individual. Therefore it is of high importance that people suffering from this disease still get the right amount of dental hygiene.
Because of the weakness of the muscles, a patient may not be able to brush his own teeth. As such, he may require the assistance of another person preferably from a well-trained professional like a caregiver. An expert assistance is necessary to make sure that the patient gets the best dental hygiene even for his condition. This may mean brushing the patient’s teeth, flossing them and administering any required medicines.
Another important point to consider is that some Parkinson’s Disease patients are prescribed to take drugs that can cause xerostomia. Xerostomia is more commonly called dry mouth. The saliva is an important component of a good oral hygiene as it helps clean the mouth by fighting off bacteria. Now, a person who suffers from xerostomia has higher risk of developing tooth decay, halitosis and other periodontal diseases and disorders. If you have constant dry mouth, your dentist can prescribe you with a medicine that can stimulate the production of more saliva as well as prescribing you with fluoride treatments to help battle tooth decay.
Also, due to the fact that Parkinson’s Disease patients may suffer from tremors, muscle rigidity and weakness, as well as feel agitated, it will be harder to keep him still in the dentist’s chair. This is very important because it makes it harder for the dentist to conduct the necessary dental procedures. Some form of equipment and contraptions may be used to keep the patient still. For much worse situations, the dentist may require to sedate his patient to avoid any unnecessary movements during the treatment.
If you want to learn more about Parkinsons disease and its implications when it comes to oral health get straight answers from professionals who also provide info on the correlation between Osseous Surgery and dental health, visit us at http://www.cosmeticdentistryguide.co.uk
Immune system gene linked with Parkinson’s: study
A gene linked with the immune system may play a role in developing Parkinson’s disease, researchers said on Sunday, marking a possible advance in the search for effective treatments. Read more on Reuters via Yahoo! News
Question by Courtney: What is the genetic basis for Parkinson’s Disease?
I am currently working on a project for my biology class on parkinson’s disease. in one of the boxes i have to put the genetic basis for PD.
(for example, is it sex linked, controlled by one or multiple alleles, non disjunction, random mutation of a certain gene, etc.)
I can’t seem to find these answers anywhere.
Any answers or suggestions of sites would be great, thanks.
Best answer:
Answer by Mags The jury is still out for the full genetic basis for PD.
The latest concept is that Parkinson’s disease is genetic and can remain dormant for generations. One reason that PD was not thought to be primarily or strictly genetic in nature was that sometimes many generations were skipped. It is possible that other factors have to act as the trigger. Environmental, medications, heavy metal exposure and the like.
I put the best link last but read down first as the expository info will be in the earlier links.
The first link is for two studies completed in 2008 by two researchers from the Mayo clinic where PD studies have been conducted for many years.
In one study a mutation of LRRK2-R1628P has been traced back to 2,500 BC. LRRK2-G2385R has been traced back 4,500 years.
Another study found that LRRK2-R1441C can increase the chances of developing PD by 10X.
http://www.scientistlive.com/European-Sc…
Next let’s go to the LRRK2 (leucine-rich repeat kinease2) autosomal dominant mutation which you can read about here for starters because it has been identified in almost 5% of PD cases:
http://www.thelancet.com/journals/lancet…
There is a study currently recruiting for a LRRK2 study in Maryland:
http://clinicaltrials.gov/ct2/show/NCT00…
Glucocerebrosidase gene
GBA mutations (N370S, L444P, 84GG, IVS+1, V394L, and R496H) that are most common among Ashkenazi Jews
http://www.thelancet.com/journals/laneur…
70117-0/abstract
and GBA-Gly2019SER here:
http://content.nejm.org/cgi/content/shor…
A study published in 2007 indicated that genetic mutations were 2X as common in YOPD (Young or early onset Parkinson’s Disease) and in people of Jewish Ancestry – specifically Ashkenazic)
Here is an abstract link about DJ-1, an autosomal recessive linked to PD. The abstract also references PARK6 and PARK7:
http://jnnp.bmj.com/cgi/content/abstract…
The best gene data base is here – it is a public and you can link to the site to see it:
http://datam.i2r.a-star.edu.sg/mdpd/stat…
In this chart you will see the gene, the number of reports and ethnic groups
Naturally it begins with LRRK2. PARK2 followed by SNCA, CYP2D6, PINK1, MAPT, UCHL1, MAOB, PARK7 and APOE
It then lists the top 10 genes with the most variants followed by the top 10 with the most negative reports.
There are several other comparisons you can do at the site, it is amazing. Check it out.
While it is true that more men than women develop PD that may be because of a bioprotectiveness of estrogen. Which of course ends at sometime with menopause.
You should probably search for Chinese – HAN – gene – Parkinson’s disease. You might find the rest of the answer which you need. There are also several familial studies. I have read the abstracts but not the full studies.
Here are a few which should help:
http://www.ncbi.nlm.nih.gov/pubmed/12730996
Here’s a familial study from Italy but it is older, 2003:
To properly search just enter each term with Parkinson’s disease and you will find a host of abstracts and some articles about the abstracts. You will not find definitive answers because they aren’t there yet. Pd is a complicated disease.
Give your answer to this question below!
Stretching for the Parkinson’s 5K Walk and Fun Run 2008
PROJECT: ON/OFF Living & Coping with Young O nset Parkinson’s Disease Directed, produced, filmed, and edited by Tim Costello. THIS IS A SHORT, NON FINAL PRODCUT, USED AS A TEASER USED TO FIND THE FUNDING NEEDED, 000, TO FINISH THE PROJECT (ONE HOUR DOCUMENTARY). FINAL PROJECT WILL DOCUMENT 6 YOUNG ONSET “LIVING” VICE “SUFFERING” FROM PARKINSON’S DISEASE. FILMMAKER: Tim Costello PROJECT IDEA DEVOLOPED BY: TOM BERDINE SPONSOR/FUND SOURCE: TBD FACTS It is estim ated that 1.5 m illion Am ericans are currently diagnosed w ith Parkinson’s disease. 50000 to 60000 more are diagnosed each year. It is believed that 10% of these are under 49, w ith a good m ajority in their late teens, 20′s, 30′s, and 40′s. These individuals are graduating college, starting careers, relationships, families, and trying to build a future for themselves and their loved ones. These are referred to as being diagnosed as “young onset”. ABOUT THE PROJECT The film project is a documentary that will give the audience a front row seat into the normally private lives of six people diagnosed w ith young onset Parkinson’s disease. The film w ill be unscripted, real, at times humorous and other times shocking. It will show them living life as close to or better then before diagnosis. It will show them accommodating these symptoms and side effects despite the daily challenges thrown at them by the symptoms of the disease and side effects of the various medications.
The Repercussions of Parkinson’s Disease in Oral Health
An estimated 50,000 Americans are diagnosed with Parkinson’s Disease each year. It generally affects people in their middle to late years. It is a kind of disorder that causes uncontrollable muscle movements, tremors, muscle rigidity and may even lead to severe memory loss. The patient’s speech and motors skills can also suffer.
Parkinson’s Disease is a degenerative disorder that affects the body’s nervous system which in turn is responsible for the relay of communication between the brain and the muscles. A disruption occurs in the nervous system that gravely affects reactions and movements of the muscles leading to such abnormalities as tremors and rigidity.
The disease usually starts to show symptoms with just a few individual muscle tremors. Sometimes it can manifest itself due to lack of muscle controls that are gradually visible to other people. This can be lack of facial expressions, mumbling sounds while talking, and even the non-movement of the arms while walking. These are simple symptoms that may usually mean the starting occurrence of Parkinson’s Disease.
A patient suffering from this disease may likewise suffer from very poor dental hygiene. While it is true that most people who have Parkinson’s Disease are already old and therefore no longer requires a set of perfect teeth, the fact remains that oral health is an important factor on the overall health condition of an individual. Therefore it is of high importance that people suffering from this disease still get the right amount of dental hygiene.
Because of the weakness of the muscles, a patient may not be able to brush his own teeth. As such, he may require the assistance of another person preferably from a well-trained professional like a caregiver. An expert assistance is necessary to make sure that the patient gets the best dental hygiene even for his condition. This may mean brushing the patient’s teeth, flossing them and administering any required medicines.
Another important point to consider is that some Parkinson’s Disease patients are prescribed to take drugs that can cause xerostomia. Xerostomia is more commonly called dry mouth. The saliva is an important component of a good oral hygiene as it helps clean the mouth by fighting off bacteria. Now, a person who suffers from xerostomia has higher risk of developing tooth decay, halitosis and other periodontal diseases and disorders. If you have constant dry mouth, your dentist can prescribe you with a medicine that can stimulate the production of more saliva as well as prescribing you with fluoride treatments to help battle tooth decay.
Also, due to the fact that Parkinson’s Disease patients may suffer from tremors, muscle rigidity and weakness, as well as feel agitated, it will be harder to keep him still in the dentist’s chair. This is very important because it makes it harder for the dentist to conduct the necessary dental procedures. Some form of equipment and contraptions may be used to keep the patient still. For much worse situations, the dentist may require to sedate his patient to avoid any unnecessary movements during the treatment.
If you want to learn more about Parkinsons disease and its implications when it comes to oral health get straight answers from professionals who also provide info on the correlation between Osseous Surgery and dental health, visit us at http://www.cosmeticdentistryguide.co.uk
Human Induced Pluripotent Stem Cells Successfully Used to Treat Parkinson’s in Rodents
Researchers at the Buck Institute for Age Research have successfully used human induced pluripotent stem cells (iPSCs) to treat rodents afflicted with Parkinson’s Disease (PD). The research validates a scalable protocol that can be used to manufacture the type of neurons needed to treat the disease and paves the way for the use of iPSC’s in various biomedical applications. Read more on Newswise
Question by Courtney: What is the genetic basis for Parkinson’s Disease?
I am currently working on a project for my biology class on parkinson’s disease. in one of the boxes i have to put the genetic basis for PD.
(for example, is it sex linked, controlled by one or multiple alleles, non disjunction, random mutation of a certain gene, etc.)
I can’t seem to find these answers anywhere.
Any answers or suggestions of sites would be great, thanks.
Best answer:
Answer by Mags The jury is still out for the full genetic basis for PD.
The latest concept is that Parkinson’s disease is genetic and can remain dormant for generations. One reason that PD was not thought to be primarily or strictly genetic in nature was that sometimes many generations were skipped. It is possible that other factors have to act as the trigger. Environmental, medications, heavy metal exposure and the like.
I put the best link last but read down first as the expository info will be in the earlier links.
The first link is for two studies completed in 2008 by two researchers from the Mayo clinic where PD studies have been conducted for many years.
In one study a mutation of LRRK2-R1628P has been traced back to 2,500 BC. LRRK2-G2385R has been traced back 4,500 years.
Another study found that LRRK2-R1441C can increase the chances of developing PD by 10X.
http://www.scientistlive.com/European-Sc…
Next let’s go to the LRRK2 (leucine-rich repeat kinease2) autosomal dominant mutation which you can read about here for starters because it has been identified in almost 5% of PD cases:
http://www.thelancet.com/journals/lancet…
There is a study currently recruiting for a LRRK2 study in Maryland:
http://clinicaltrials.gov/ct2/show/NCT00…
Glucocerebrosidase gene
GBA mutations (N370S, L444P, 84GG, IVS+1, V394L, and R496H) that are most common among Ashkenazi Jews
http://www.thelancet.com/journals/laneur…
70117-0/abstract
and GBA-Gly2019SER here:
http://content.nejm.org/cgi/content/shor…
A study published in 2007 indicated that genetic mutations were 2X as common in YOPD (Young or early onset Parkinson’s Disease) and in people of Jewish Ancestry – specifically Ashkenazic)
Here is an abstract link about DJ-1, an autosomal recessive linked to PD. The abstract also references PARK6 and PARK7:
http://jnnp.bmj.com/cgi/content/abstract…
The best gene data base is here – it is a public and you can link to the site to see it:
http://datam.i2r.a-star.edu.sg/mdpd/stat…
In this chart you will see the gene, the number of reports and ethnic groups
Naturally it begins with LRRK2. PARK2 followed by SNCA, CYP2D6, PINK1, MAPT, UCHL1, MAOB, PARK7 and APOE
It then lists the top 10 genes with the most variants followed by the top 10 with the most negative reports.
There are several other comparisons you can do at the site, it is amazing. Check it out.
While it is true that more men than women develop PD that may be because of a bioprotectiveness of estrogen. Which of course ends at sometime with menopause.
You should probably search for Chinese – HAN – gene – Parkinson’s disease. You might find the rest of the answer which you need. There are also several familial studies. I have read the abstracts but not the full studies.
Here are a few which should help:
http://www.ncbi.nlm.nih.gov/pubmed/12730996
Here’s a familial study from Italy but it is older, 2003:
To properly search just enter each term with Parkinson’s disease and you will find a host of abstracts and some articles about the abstracts. You will not find definitive answers because they aren’t there yet. Pd is a complicated disease.
What do you think? Answer below!
Stretching for the Parkinson’s 5K Walk and Fun Run 2008
PROJECT: ON/OFF Living & Coping with Young O nset Parkinson’s Disease Directed, produced, filmed, and edited by Tim Costello. THIS IS A SHORT, NON FINAL PRODCUT, USED AS A TEASER USED TO FIND THE FUNDING NEEDED, 000, TO FINISH THE PROJECT (ONE HOUR DOCUMENTARY). FINAL PROJECT WILL DOCUMENT 6 YOUNG ONSET “LIVING” VICE “SUFFERING” FROM PARKINSON’S DISEASE. FILMMAKER: Tim Costello PROJECT IDEA DEVOLOPED BY: TOM BERDINE SPONSOR/FUND SOURCE: TBD FACTS It is estim ated that 1.5 m illion Am ericans are currently diagnosed w ith Parkinson’s disease. 50000 to 60000 more are diagnosed each year. It is believed that 10% of these are under 49, w ith a good m ajority in their late teens, 20′s, 30′s, and 40′s. These individuals are graduating college, starting careers, relationships, families, and trying to build a future for themselves and their loved ones. These are referred to as being diagnosed as “young onset”. ABOUT THE PROJECT The film project is a documentary that will give the audience a front row seat into the normally private lives of six people diagnosed w ith young onset Parkinson’s disease. The film w ill be unscripted, real, at times humorous and other times shocking. It will show them living life as close to or better then before diagnosis. It will show them accommodating these symptoms and side effects despite the daily challenges thrown at them by the symptoms of the disease and side effects of the various medications. Video Rating: 4 / 5
Parkinson’s Disease – The Symptoms Of The Disease
As an adult, you have to prepare yourself for any calamity coming your way. A few thins will be inevitable when you get old. But in spite of your awareness and preparation, there are a few diseases which cannot be stopped from attacking you. Parkinsonâs disease is one such disease which you cannot prepare for. It mainly attacks elder persons though younger people are also liable to be attacked by it. Medically, it is related to the brain but most of them believe it occurs because of mental degeneration. It can be extremely stressful to watch a person suffering from his type of disease as it progressively deteriorates the condition. The elder will only know the starting point of this disease as it all happens in a hurry after that.
Nerve cells in a body cause Parkinsonâs disease. They slowly break down and thus preventing any signal conveyance to the brain. The nerve cells connect the body and the brain and let the brain know what the body is doing or vice versa. This disease can prevent this from happening as the nerve cells get damaged slowly. Sufferer starts to lose control over things and it becomes extremely difficult to manage his body.
Symptoms are plenty for this kind of a disease. Earliest of the symptoms could be the shaking of arms, hands, legs and jaw of a person. Nerves which are deteriorating affect the muscles and its movement. These symptoms can get worse as time goes by and it becomes noticeable to people around you. The disease affects one part of the body more than the other and it affects al sorts of communications. The tremors not only cause the nerves to weaken more, but also affect the speech of the person. The big shakes of hands and legs usually start after a year of tremors continuously for a few. Sometimes, for a few sufferers it takes hardly any time before these tremors strike them.
Doctors, as of yet, do not know how this Parkinsonâs disease is caused despite the extensive and extravagant researches being done. Right now, there is no real test to diagnose this disease in a patient. The diagnosis done is based on medical histories and the tests taken to rule out other illnesses and ailments. This basically means there is no cure for this disease. So once if you have acquired this disease, it is going to be there for life. Many try to get used to it and resume their daily activities, but there will be a point when it can get terrible and intolerable. It mainly causes depression in people as they find it difficult to go about their daily work. Dressing and unbuttoning could be like the impossible mazes to conquer.
One can alleviate the symptoms of Parkinsonâs disease using certain drugs. This is only for a short term though. A few medications have the effect of stopping the tremors for some period of time and thus helping the sufferers to go on with their normal life. There are certain drugs available in the market. Carbidopa-levodopa, Selegiline, Bromocriptine, Ropinirole, Pergolide and Tolcapone are a few drugs which helps the above case. Though they have different brand names, they are slated to do the same work. These drugs donât suit everyone. A few tend to get better with these while a few suffer more at the hands of these drugs. No body knows which work better so even the doctors take chances.
Parkinsonâs disease is something no one should get as it can disturb not only the sufferer but also the people around. There is very little that could be done to save people from this terrible disease. If diagnosed early, it can prove to be effective though it can sometimes go out of hand. Research is still going on to find a cure. Till then you and I have no choice but to get on with life.
Abhishek successfully runs an Old Age Home and he has got some great Eldercare Secrets up his sleeves! Download his FREE 80 Pages Ebook, “How To Take Great Care Of Elders” from his website http://www.Senior-Guides.com/560/index.htm . Only limited Free Copies available.
Roots Producer David Wolper Dies at 82
David Wolper , producer of the celebrated miniseries Roots , has died of congestive heart disease and complications of Parkinson’s disease, according to The Associated Press . He was 82. Wolper is perhaps best known for his work on the 1977 ABC miniseries that followed… Read More Other Links From TVGuide.com Willy Wonka And The Chocolate Factory This Is Elvis L.A. Confidential Imagine: John … Read more on TV Guide
Question by M.K.: since dopamine is transferred to your body when smoking weed, does it do good to parkinson’s disease sufferers?
“The primary symptoms are the results of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain.” -Wikipedia
my grandfather has parkinson’s disease, but is really chill. would him smoking weed help his disease at all? because parkinsons is a disease that is caused by “insufficient formation and action” would smoking pot help him?
Best answer:
Answer by Liron A connection similar to this has been reported before. The study attached claimed that smoking cured Alzheimer”s.
What the authors fail to realise is that the greater incidence of parkinson”s in non-smokers is not proof of smoking being a cure. It is quite the opposite. Smokers don”t live long enough to get this type of degenerative disease. It is one more proof that smoking kills. Nothing else.
Sorry to hear about your grandfather. My grandfather has parkinson’s too.
PROJECT: ON/OFF Living & Coping with Young O nset Parkinson’s Disease Directed, produced, filmed, and edited by Tim Costello. THIS IS A SHORT, NON FINAL PRODCUT, USED AS A TEASER USED TO FIND THE FUNDING NEEDED, 000, TO FINISH THE PROJECT (ONE HOUR DOCUMENTARY). FINAL PROJECT WILL DOCUMENT 6 YOUNG ONSET “LIVING” VICE “SUFFERING” FROM PARKINSON’S DISEASE. FILMMAKER: Tim Costello PROJECT IDEA DEVOLOPED BY: TOM BERDINE SPONSOR/FUND SOURCE: TBD FACTS It is estim ated that 1.5 m illion Am ericans are currently diagnosed w ith Parkinson’s disease. 50000 to 60000 more are diagnosed each year. It is believed that 10% of these are under 49, w ith a good m ajority in their late teens, 20′s, 30′s, and 40′s. These individuals are graduating college, starting careers, relationships, families, and trying to build a future for themselves and their loved ones. These are referred to as being diagnosed as “young onset”. ABOUT THE PROJECT The film project is a documentary that will give the audience a front row seat into the normally private lives of six people diagnosed w ith young onset Parkinson’s disease. The film w ill be unscripted, real, at times humorous and other times shocking. It will show them living life as close to or better then before diagnosis. It will show them accommodating these symptoms and side effects despite the daily challenges thrown at them by the symptoms of the disease and side effects of the various medications. Video Rating: 4 / 5
Parkinson’s Disease – The Symptoms Of The Disease
As an adult, you have to prepare yourself for any calamity coming your way. A few thins will be inevitable when you get old. But in spite of your awareness and preparation, there are a few diseases which cannot be stopped from attacking you. Parkinsonâs disease is one such disease which you cannot prepare for. It mainly attacks elder persons though younger people are also liable to be attacked by it. Medically, it is related to the brain but most of them believe it occurs because of mental degeneration. It can be extremely stressful to watch a person suffering from his type of disease as it progressively deteriorates the condition. The elder will only know the starting point of this disease as it all happens in a hurry after that.
Nerve cells in a body cause Parkinsonâs disease. They slowly break down and thus preventing any signal conveyance to the brain. The nerve cells connect the body and the brain and let the brain know what the body is doing or vice versa. This disease can prevent this from happening as the nerve cells get damaged slowly. Sufferer starts to lose control over things and it becomes extremely difficult to manage his body.
Symptoms are plenty for this kind of a disease. Earliest of the symptoms could be the shaking of arms, hands, legs and jaw of a person. Nerves which are deteriorating affect the muscles and its movement. These symptoms can get worse as time goes by and it becomes noticeable to people around you. The disease affects one part of the body more than the other and it affects al sorts of communications. The tremors not only cause the nerves to weaken more, but also affect the speech of the person. The big shakes of hands and legs usually start after a year of tremors continuously for a few. Sometimes, for a few sufferers it takes hardly any time before these tremors strike them.
Doctors, as of yet, do not know how this Parkinsonâs disease is caused despite the extensive and extravagant researches being done. Right now, there is no real test to diagnose this disease in a patient. The diagnosis done is based on medical histories and the tests taken to rule out other illnesses and ailments. This basically means there is no cure for this disease. So once if you have acquired this disease, it is going to be there for life. Many try to get used to it and resume their daily activities, but there will be a point when it can get terrible and intolerable. It mainly causes depression in people as they find it difficult to go about their daily work. Dressing and unbuttoning could be like the impossible mazes to conquer.
One can alleviate the symptoms of Parkinsonâs disease using certain drugs. This is only for a short term though. A few medications have the effect of stopping the tremors for some period of time and thus helping the sufferers to go on with their normal life. There are certain drugs available in the market. Carbidopa-levodopa, Selegiline, Bromocriptine, Ropinirole, Pergolide and Tolcapone are a few drugs which helps the above case. Though they have different brand names, they are slated to do the same work. These drugs donât suit everyone. A few tend to get better with these while a few suffer more at the hands of these drugs. No body knows which work better so even the doctors take chances.
Parkinsonâs disease is something no one should get as it can disturb not only the sufferer but also the people around. There is very little that could be done to save people from this terrible disease. If diagnosed early, it can prove to be effective though it can sometimes go out of hand. Research is still going on to find a cure. Till then you and I have no choice but to get on with life.
Abhishek successfully runs an Old Age Home and he has got some great Eldercare Secrets up his sleeves! Download his FREE 80 Pages Ebook, “How To Take Great Care Of Elders” from his website http://www.Senior-Guides.com/560/index.htm . Only limited Free Copies available.
Roots Producer David Wolper Dies at 82
David Wolper , producer of the celebrated miniseries Roots , has died of congestive heart disease and complications of Parkinson’s disease, according to The Associated Press . He was 82. Wolper is perhaps best known for his work on the 1977 ABC miniseries that followed… Read More Other Links From TVGuide.com Willy Wonka And The Chocolate Factory This Is Elvis L.A. Confidential Imagine: John … Read more on TV Guide
Question by M.K.: since dopamine is transferred to your body when smoking weed, does it do good to parkinson’s disease sufferers?
“The primary symptoms are the results of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain.” -Wikipedia
my grandfather has parkinson’s disease, but is really chill. would him smoking weed help his disease at all? because parkinsons is a disease that is caused by “insufficient formation and action” would smoking pot help him?
Best answer:
Answer by Liron A connection similar to this has been reported before. The study attached claimed that smoking cured Alzheimer”s.
What the authors fail to realise is that the greater incidence of parkinson”s in non-smokers is not proof of smoking being a cure. It is quite the opposite. Smokers don”t live long enough to get this type of degenerative disease. It is one more proof that smoking kills. Nothing else.
Sorry to hear about your grandfather. My grandfather has parkinson’s too.
PROJECT: ON/OFF Living & Coping with Young O nset Parkinson’s Disease Directed, produced, filmed, and edited by Tim Costello. THIS IS A SHORT, NON FINAL PRODCUT, USED AS A TEASER USED TO FIND THE FUNDING NEEDED, 000, TO FINISH THE PROJECT (ONE HOUR DOCUMENTARY). FINAL PROJECT WILL DOCUMENT 6 YOUNG ONSET “LIVING” VICE “SUFFERING” FROM PARKINSON’S DISEASE. FILMMAKER: Tim Costello PROJECT IDEA DEVOLOPED BY: TOM BERDINE SPONSOR/FUND SOURCE: TBD FACTS It is estim ated that 1.5 m illion Am ericans are currently diagnosed w ith Parkinson’s disease. 50000 to 60000 more are diagnosed each year. It is believed that 10% of these are under 49, w ith a good m ajority in their late teens, 20′s, 30′s, and 40′s. These individuals are graduating college, starting careers, relationships, families, and trying to build a future for themselves and their loved ones. These are referred to as being diagnosed as “young onset”. ABOUT THE PROJECT The film project is a documentary that will give the audience a front row seat into the normally private lives of six people diagnosed w ith young onset Parkinson’s disease. The film w ill be unscripted, real, at times humorous and other times shocking. It will show them living life as close to or better then before diagnosis. It will show them accommodating these symptoms and side effects despite the daily challenges thrown at them by the symptoms of the disease and side effects of the various medications. Video Rating: 4 / 5
Parkinson’s Disease – The Symptoms Of The Disease
As an adult, you have to prepare yourself for any calamity coming your way. A few thins will be inevitable when you get old. But in spite of your awareness and preparation, there are a few diseases which cannot be stopped from attacking you. Parkinsonâs disease is one such disease which you cannot prepare for. It mainly attacks elder persons though younger people are also liable to be attacked by it. Medically, it is related to the brain but most of them believe it occurs because of mental degeneration. It can be extremely stressful to watch a person suffering from his type of disease as it progressively deteriorates the condition. The elder will only know the starting point of this disease as it all happens in a hurry after that.
Nerve cells in a body cause Parkinsonâs disease. They slowly break down and thus preventing any signal conveyance to the brain. The nerve cells connect the body and the brain and let the brain know what the body is doing or vice versa. This disease can prevent this from happening as the nerve cells get damaged slowly. Sufferer starts to lose control over things and it becomes extremely difficult to manage his body.
Symptoms are plenty for this kind of a disease. Earliest of the symptoms could be the shaking of arms, hands, legs and jaw of a person. Nerves which are deteriorating affect the muscles and its movement. These symptoms can get worse as time goes by and it becomes noticeable to people around you. The disease affects one part of the body more than the other and it affects al sorts of communications. The tremors not only cause the nerves to weaken more, but also affect the speech of the person. The big shakes of hands and legs usually start after a year of tremors continuously for a few. Sometimes, for a few sufferers it takes hardly any time before these tremors strike them.
Doctors, as of yet, do not know how this Parkinsonâs disease is caused despite the extensive and extravagant researches being done. Right now, there is no real test to diagnose this disease in a patient. The diagnosis done is based on medical histories and the tests taken to rule out other illnesses and ailments. This basically means there is no cure for this disease. So once if you have acquired this disease, it is going to be there for life. Many try to get used to it and resume their daily activities, but there will be a point when it can get terrible and intolerable. It mainly causes depression in people as they find it difficult to go about their daily work. Dressing and unbuttoning could be like the impossible mazes to conquer.
One can alleviate the symptoms of Parkinsonâs disease using certain drugs. This is only for a short term though. A few medications have the effect of stopping the tremors for some period of time and thus helping the sufferers to go on with their normal life. There are certain drugs available in the market. Carbidopa-levodopa, Selegiline, Bromocriptine, Ropinirole, Pergolide and Tolcapone are a few drugs which helps the above case. Though they have different brand names, they are slated to do the same work. These drugs donât suit everyone. A few tend to get better with these while a few suffer more at the hands of these drugs. No body knows which work better so even the doctors take chances.
Parkinsonâs disease is something no one should get as it can disturb not only the sufferer but also the people around. There is very little that could be done to save people from this terrible disease. If diagnosed early, it can prove to be effective though it can sometimes go out of hand. Research is still going on to find a cure. Till then you and I have no choice but to get on with life.
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TEMPO Study Further Demonstrates The Benefits Of Azilect® In Early Parkinson’s Disease Patients
H. Lundbeck A/S (Lundbeck) and Teva Pharmaceutical Industries Ltd. (NASDAQ: TEVA) announced newly published long-term data on Azilect® (rasagiline tablets) from the TEMPO study and its open-label extension. The findings confirm the long-term efficacy, safety and tolerability of Azilect® in patients with Parkinson’s disease (PD) and further demonstrate the benefits obtained with early treatment … Read more on Medical News Today
Question by M.K.: since dopamine is transferred to your body when smoking weed, does it do good to parkinson’s disease sufferers?
“The primary symptoms are the results of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain.” -Wikipedia
my grandfather has parkinson’s disease, but is really chill. would him smoking weed help his disease at all? because parkinsons is a disease that is caused by “insufficient formation and action” would smoking pot help him?
Best answer:
Answer by Liron A connection similar to this has been reported before. The study attached claimed that smoking cured Alzheimer”s.
What the authors fail to realise is that the greater incidence of parkinson”s in non-smokers is not proof of smoking being a cure. It is quite the opposite. Smokers don”t live long enough to get this type of degenerative disease. It is one more proof that smoking kills. Nothing else.
Sorry to hear about your grandfather. My grandfather has parkinson’s too.
PROJECT: ON/OFF Living & Coping with Young O nset Parkinson’s Disease Directed, produced, filmed, and edited by Tim Costello. THIS IS A SHORT, NON FINAL PRODCUT, USED AS A TEASER USED TO FIND THE FUNDING NEEDED, 000, TO FINISH THE PROJECT (ONE HOUR DOCUMENTARY). FINAL PROJECT WILL DOCUMENT 6 YOUNG ONSET “LIVING” VICE “SUFFERING” FROM PARKINSON’S DISEASE. FILMMAKER: Tim Costello PROJECT IDEA DEVOLOPED BY: TOM BERDINE SPONSOR/FUND SOURCE: TBD FACTS It is estim ated that 1.5 m illion Am ericans are currently diagnosed w ith Parkinson’s disease. 50000 to 60000 more are diagnosed each year. It is believed that 10% of these are under 49, w ith a good m ajority in their late teens, 20′s, 30′s, and 40′s. These individuals are graduating college, starting careers, relationships, families, and trying to build a future for themselves and their loved ones. These are referred to as being diagnosed as “young onset”. ABOUT THE PROJECT The film project is a documentary that will give the audience a front row seat into the normally private lives of six people diagnosed w ith young onset Parkinson’s disease. The film w ill be unscripted, real, at times humorous and other times shocking. It will show them living life as close to or better then before diagnosis. It will show them accommodating these symptoms and side effects despite the daily challenges thrown at them by the symptoms of the disease and side effects of the various medications. Video Rating: 4 / 5
Coping Mechanisms for Parkinson’s Disease
Some years ago the famous American actor Michael J. Fox made headlines when he revealed that he was suffering from Parkinson’s Disease. While many assume that this disease is one that affects only the elderly, Mr. Fox demonstrated personally how this condition can really affect anyone at any time, and he did quite a bit of good in bringing the disease to the attention of the general public.
Parkinson’s Disease is also called shaking palsy. The cause is not known but it appears that when an imbalance of two substances in the brain, dopamine and acetylcholine, exist then the symptoms of this disease are present. These two substances are need to transmit messages between the nerve cells and the muscles throughout the body. When the amount of dopamine in the brain is somehow decreased the nerve signals in the brain become confused.
Dopamine assists with muscle control and without it the body has a hard time controlling its own movements. Those with this disease usually have severe trembling in the hands, arms, legs, the areas of their face, or may experience rigidity and stiffness of their limbs and they may also have problems with incontinence. Typically they also have a slowness of movement and problems with posture and balance. As the disease progresses the patient may have trouble walking, talking, and with other everyday tasks. Extreme cases of the disease may result in difficulty with chewing and swallowing, and even speaking.
Treating Parkinson’s Disease
As of now there is no cure for the disease but there are many treatment options available. Medications can help with dopamine production by stimulating the nerves responsible for this. Other medications can help with the symptoms of Parkinson’s Disease by stimulating the muscles so that rigidity is reduces. Other may help with tremor. In some cases there may be surgeries that one can undergo; electrodes can be implanted into the brain so that certain areas are stimulated.
Other Options
Parkinson’s Disease can be very difficult for the patient; not being able to control one’s movements can make even the smallest of tasks very difficult. However, understanding one’s limitations is the first step toward coping and treating the disease. A patient may need to make accommodations around the house and the office. Installing rails in the bathroom can help. When swallowing becomes difficult it’s time to slow down around mealtime and take your time. Smaller bites and liquid foods are advisable. Some employers will accommodate those with this disease by allowing them to use computers that respond to voice commands so that typing is no longer as necessary. Other adjustments can be made to one’s place of employment as well; moving a desk or work space closer to the restroom and using the phone and email instead of needing to show up in person for conferences and meetings can help as well. These are small changes but can make a big difference for the one with this disabling disease.
It’s good to let friends and family know if you have Parkinson’s Disease so they can readily assist with chores, and talk to your doctor about getting assistance from visiting nurses and other help.
Always consult your doctor before using this information.
This Article is nutritional in nature and is not to be construed as medical advice.
David Cowley has created numerous articles about the relationship between diseases and vitamins. Visit Health Related Articles
TEMPO Study Further Demonstrates The Benefits Of Azilect® In Early Parkinson’s Disease Patients
H. Lundbeck A/S (Lundbeck) and Teva Pharmaceutical Industries Ltd. (NASDAQ: TEVA) announced newly published long-term data on Azilect® (rasagiline tablets) from the TEMPO study and its open-label extension. The findings confirm the long-term efficacy, safety and tolerability of Azilect® in patients with Parkinson’s disease (PD) and further demonstrate the benefits obtained with early treatment … Read more on Medical News Today
Question by M.K.: since dopamine is transferred to your body when smoking weed, does it do good to parkinson’s disease sufferers?
“The primary symptoms are the results of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain.” -Wikipedia
my grandfather has parkinson’s disease, but is really chill. would him smoking weed help his disease at all? because parkinsons is a disease that is caused by “insufficient formation and action” would smoking pot help him?
Best answer:
Answer by Liron A connection similar to this has been reported before. The study attached claimed that smoking cured Alzheimer”s.
What the authors fail to realise is that the greater incidence of parkinson”s in non-smokers is not proof of smoking being a cure. It is quite the opposite. Smokers don”t live long enough to get this type of degenerative disease. It is one more proof that smoking kills. Nothing else.
Sorry to hear about your grandfather. My grandfather has parkinson’s too.
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Band Playing at the half way mark at the Parkinson’s 5k Walk and Fun Run
suffers from Parkinson's disease, then this is going to be one of the most important things you'll ever read.
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