Comments on: your patient with parkinson’s disease is taking metoclopramide for GERD.? http://parkinsondiseasetreatment.com/your-patient-with-parkinsons-disease-is-taking-metoclopramide-for-gerd.html Tue, 07 Sep 2010 02:24:03 +0000 http://wordpress.org/?v=2.7 hourly 1 By: Mags http://parkinsondiseasetreatment.com/your-patient-with-parkinsons-disease-is-taking-metoclopramide-for-gerd.html/comment-page-1#comment-1291 Mags Mon, 09 Nov 2009 05:29:28 +0000 http://parkinsondiseasetreatment.com/your-patient-with-parkinsons-disease-is-taking-metoclopramide-for-gerd.html#comment-1291 c. Dopamine antagonists are seldom used for Parkinson's disease any longer. They are used as anti-psychotics for PD primarily. They most certainly wouldn't be a first line medication for GERD in a PD patient. That said there might be some benefit to the action of metoclopramide in the case of the common digestive issues of PD as it does increase muscle contraction of the upper GI tract. a) is true b) is also a precautionary warning d) is another warning about dopamine antagonists which bind to the dopamine receptors but do not stimulate them. Because the PD medication (drug interactions) of this patient is unknown in the question, the statemtment is also true. Take a look at this abstract to see if it provides additional insight into the correct answer. http://www3.interscience.wiley.com/journal/118506024/abstract?CRETRY=1&SRETRY=0 While there might be a reason for prescribing it, it would never be a first line treatment for a PD patient as defined in the question. c. Dopamine antagonists are seldom used for Parkinson’s disease any longer. They are used as anti-psychotics for PD primarily. They most certainly wouldn’t be a first line medication for GERD in a PD patient.

That said there might be some benefit to the action of metoclopramide in the case of the common digestive issues of PD as it does increase muscle contraction of the upper GI tract.

a) is true
b) is also a precautionary warning
d) is another warning about dopamine antagonists which bind to the dopamine receptors but do not stimulate them. Because the PD medication (drug interactions) of this patient is unknown in the question, the statemtment is also true.

Take a look at this abstract to see if it provides additional insight into the correct answer.
http://www3.interscience.wiley.com/journal/118506024/abstract?CRETRY=1&SRETRY=0

While there might be a reason for prescribing it, it would never be a first line treatment for a PD patient as defined in the question.

]]> By: aneurodoc125 http://parkinsondiseasetreatment.com/your-patient-with-parkinsons-disease-is-taking-metoclopramide-for-gerd.html/comment-page-1#comment-1292 aneurodoc125 Mon, 09 Nov 2009 05:29:28 +0000 http://parkinsondiseasetreatment.com/your-patient-with-parkinsons-disease-is-taking-metoclopramide-for-gerd.html#comment-1292 Dopamine antagonists cause Parkinsonian-like symptoms. The correct answer is D. http://www.accessdata.fda.gov/drugsatfda_docs/label/2009/017854s052,021793s005medguide.pdf Dopamine antagonists cause Parkinsonian-like symptoms. The correct answer is D.
http://www.accessdata.fda.gov/drugsatfda_docs/label/2009/017854s052,021793s005medguide.pdf

]]> By: gunnersluver http://parkinsondiseasetreatment.com/your-patient-with-parkinsons-disease-is-taking-metoclopramide-for-gerd.html/comment-page-1#comment-1293 gunnersluver Mon, 09 Nov 2009 05:29:28 +0000 http://parkinsondiseasetreatment.com/your-patient-with-parkinsons-disease-is-taking-metoclopramide-for-gerd.html#comment-1293 D. for sure this drug surely worsens symptoms of anything you have. I was prescribed metoclopramide for digesting food faster but instead I had a dystonic reaction which included uncontrolled muscle movements in tongue and jaw. Worst feeling you could ever imagine I was so frightened. I couldn't even talk so I had go to ER and was given an injection of Benadryl to relax and cure it. I know for sure I won't be even using this drug anymore. D. for sure this drug surely worsens symptoms of anything you have. I was prescribed metoclopramide for digesting food faster but instead I had a dystonic reaction which included uncontrolled muscle movements in tongue and jaw. Worst feeling you could ever imagine I was so frightened. I couldn’t even talk so I had go to ER and was given an injection of Benadryl to relax and cure it. I know for sure I won’t be even using this drug anymore.

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